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JOURNAL OF HYPERTENSION (2006)
p53 regulates mitochondrial respiration
Satoaki Matoba et al.
SCIENCE (2006)
Molecular targets of dietary agents for prevention and therapy of cancer
BB Aggarwal et al.
BIOCHEMICAL PHARMACOLOGY (2006)
Uncoupling protein 2 has protective function during experimental autoimmune encephalomyelitis
S Vogler et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
IFN-induced attrition of CD8 T cells in the presence or absence of cognate antigen during the early stages of viral infections
Kapil Bahl et al.
JOURNAL OF IMMUNOLOGY (2006)
JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species
HM Shen et al.
FREE RADICAL BIOLOGY AND MEDICINE (2006)
Curcumin induces growth-arrest and apoptosis in association with the inhibition of constitutively active JAK-STAT pathway in T cell leukemia
J Rajasingh et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
The antioxidant function of the p53 tumor suppressor
AA Sablina et al.
NATURE MEDICINE (2005)
Glucose transporter 1 expression identifies a population of cycling CD4+CD8+ human thymocytes with high CXCR4-induced chemotaxis
L Swainson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
The p53-induced gene-6 (proline oxidase) mediates apoptosis through a calcineurin-dependent pathway
A Rivera et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Regulation of immune responses by L- arginine metabolism
V Bronte et al.
NATURE REVIEWS IMMUNOLOGY (2005)
Stress-induced activation of the p53 tumor suppressor in leukemia cells and normal lymphocytes requires mitochondrial activity and reactive oxygen species
L Karawajew et al.
BLOOD (2005)
Reactive oxygen species and the modulation of stroke
PJ Crack et al.
FREE RADICAL BIOLOGY AND MEDICINE (2005)
Preferential cell death of CD8+ effector memory (CCR7-CD45RA-) T cells by hydrogen peroxide-induced oxidative stress
A Takahashi et al.
JOURNAL OF IMMUNOLOGY (2005)
Estrogen regulates CCR gene expression and function in T lymphocytes
R Mo et al.
JOURNAL OF IMMUNOLOGY (2005)
Controlled elimination of intracellular H2O2:: Regulation of peroxiredoxin, catalase, and glutathione peroxidase via post-translational modification
SG Rhee et al.
ANTIOXIDANTS & REDOX SIGNALING (2005)
Anti-inflammatory properties of a chimeric recombinant superoxide dismutase: SOD2/3
D Hernandez-Saavedra et al.
BIOMEDICINE & PHARMACOTHERAPY (2005)
HIV-1 trans-activator of transcription substitutes for oxidative signaling in activation-induced T cell death
K Gülow et al.
JOURNAL OF IMMUNOLOGY (2005)
STAT1 signaling regulates tumor-associated macrophage-mediated T cell deletion
S Kusmartsev et al.
JOURNAL OF IMMUNOLOGY (2005)
N-glycosylation is necessary for enzymatic activity of a beetle (Apriona germari) cellulase
YD Wei et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Interleukin-7 in T-cell acute lymphoblastic leukemia: An extrinsic factor supporting leukemogenesis?
JT Barata et al.
LEUKEMIA & LYMPHOMA (2005)
Nitroaspirin corrects immune dysfunction in tumor-bearing hosts and promotes tumor eradication by cancer vaccination
C De Santo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
p53 prevents maturation of T cell development to the immature CD4-CD8+ stage in Bcl11b-/- mice
K Okazuka et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
The extracellular microenvironment plays a key role in regulating the redox status of cell surface proteins in HIV-infected subjects
B Sahaf et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2005)
Targeting NF-κB activation via pharmacologic inhibition of IKK2-induced apoptosis of human acute myeloid leukemia cells
C Frelin et al.
BLOOD (2005)
Antiapoptotic role of p38 mitogen activated protein kinase in Jurkat T cells and normal human T lymphocytes treated with 8-methoxypsoralen and ultraviolet-A radiation
A Cappellini et al.
APOPTOSIS (2005)
Regulation of immune cells by local. tissue oxygen tension: Hif1 alpha and adenosine receptors
M Sitkovsky et al.
NATURE REVIEWS IMMUNOLOGY (2005)
Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis
AM Cheng et al.
NUCLEIC ACIDS RESEARCH (2005)
ROS stress in cancer cells and therapeutic implications
H Pelicano et al.
DRUG RESISTANCE UPDATES (2004)
Mechanistic analysis of the immunomodulatory effects of a catalytic antioxidant on antigen-presenting cells: Implication for their use in targeting oxidation-reduction reactions in innate immunity
HM Tse et al.
FREE RADICAL BIOLOGY AND MEDICINE (2004)
Antigen-specific inhibition of CD8+ T cell response by immature myeloid cells in cancer is mediated by reactive oxygen species
S Kusmartsev et al.
JOURNAL OF IMMUNOLOGY (2004)
Retinoic acid imprints gut-homing specificity on T cells
M Iwata et al.
IMMUNITY (2004)
Mammalian antioxidant Defenses are not inducible by H2O2
S Desaint et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Rap1 signaling is required for suppression of Ras-generated reactive oxygen species and protection against oxidative stress in T lymphocytes
PHJ Remans et al.
JOURNAL OF IMMUNOLOGY (2004)
Rescuing melanoma epitope-specific cytolytic T lymphocytes from activation-induced cell death, by SP600125, an inhibitor of JNK: Implications in cancer immunotherapy
S Mehrotra et al.
JOURNAL OF IMMUNOLOGY (2004)
C242T CYBA polymorphism of the NADPH oxidase is associated with reduced respiratory burst in human neutrophils
KE Wyche et al.
HYPERTENSION (2004)
Green tea epigallocatechin-3-gallate mediates T cellular NF-κB inhibition and exerts neuroprotection in autoimmune encephalomyelitis
O Aktas et al.
JOURNAL OF IMMUNOLOGY (2004)
Central memory and effector memory T cell subsets: Function, generation, and maintenance
F Sallusto et al.
ANNUAL REVIEW OF IMMUNOLOGY (2004)
Myeloperoxidase genotype, fruit and vegetable consumption, and breast cancer risk
JY Ahn et al.
CANCER RESEARCH (2004)
Dual effect of CD4+CD25+ regulatory T cells in neurodegeneration:: A dialogue with microglia
J Kipnis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Adenovirus-mediated delivery of catalase to retinal pigment epithelial cells protects neighboring photoreceptors from photo-oxidative stress
TS Rex et al.
HUMAN GENE THERAPY (2004)
Antioxidant treatment reduces expansion and contraction of antigen-specific CD8+ T cells during primary but not secondary viral infection
NG Laniewski et al.
JOURNAL OF VIROLOGY (2004)
Nrf2 regulates the sensitivity of death receptor signals by affecting intracellular glutathione levels
N Morito et al.
ONCOGENE (2003)
Role of redox imbalance in the molecular mechanisms responsible for immunosenescence
RA Daynes et al.
ANTIOXIDANTS & REDOX SIGNALING (2003)
p53 deficiency and defective mitotic checkpoint in proliferating T lymphocytes increase chromosomal instability through aberrant exit from mitotic arrest
KH Baek et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2003)
Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents
Y Zhou et al.
BLOOD (2003)
A novel ERK-dependent signaling process that regulates interleukin-2 expression in a late phase of T cell activation
T Koike et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Lymphocyte surface thiol levels
B Sahaf et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
JNK and p38 MAP kinases in CD4+ and CD8+ T cells
M Rincón et al.
IMMUNOLOGICAL REVIEWS (2003)
Aging-induced proinflammatory shift in cytokine expression profile in rat coronary arteries
A Csiszar et al.
FASEB JOURNAL (2003)
T cell apoptosis and reactive oxygen species
DA Hildeman et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Axonal loss in the pathology of MS: consequences for understanding the progressive phase of the disease
C Bjartmar et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2003)
Influenza A virus replication is dependent on an antioxidant pathway that involves GSH and Bcl-2
L Nencioni et al.
FASEB JOURNAL (2003)
Positional identification of Ncf1 as a gene that regulates arthritis severity in rats
P Olofsson et al.
NATURE GENETICS (2003)
IL-4-induced arginase 1 suppresses alloreactive T cells in tumor-bearing mice
V Bronte et al.
JOURNAL OF IMMUNOLOGY (2003)
Impaired dopamine storage resulting from α-synuclein mutations may contribute to the pathogenesis of Parkinson's disease
J Lotharius et al.
HUMAN MOLECULAR GENETICS (2002)
Differential modulation of CD4 and CD8 T-cell proliferation by induction of nitric oxide synthesis in antigen presenting cells
RA Hoffman et al.
TRANSPLANTATION (2002)
Vitamin E inhibits CD95 ligand expression and protects T cells from activation-induced cell death
M Li-Weber et al.
JOURNAL OF CLINICAL INVESTIGATION (2002)
It's all Rel-ative:: NF-κB and CD28 costimulation of T-cell activation
LP Kane et al.
TRENDS IN IMMUNOLOGY (2002)
Persistent mitochondrial hyperpolarization, increased reactive oxygen intermediate production, and cytoplasmic alkalinization characterize altered IL-10 signaling in patients with systemic lupus erythematosus
P Gergely et al.
JOURNAL OF IMMUNOLOGY (2002)
The forkhead transcription factor FoxO regulates transcription of p27Kip1 and bim in response to IL-2
M Stahl et al.
JOURNAL OF IMMUNOLOGY (2002)
A metalloporphyrin-based superoxide dismutase mimic inhibits adoptive transfer of autoimmune diabetes by a diabetogenic T-cell clone
JD Piganelli et al.
DIABETES (2002)
Role of NQO1, MPO and CYP2E1 genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia
M Krajinovic et al.
INTERNATIONAL JOURNAL OF CANCER (2002)
Discrete generation of superoxide and hydrogen peroxide by T cell receptor stimulation: Selective regulation of mitogen-activated protein kinase activation and Fas ligand expression
S Devadas et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2002)
Chalcones from Chinese liquorice inhibit proliferation of T cells and production of cytokines
L Barfod et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2002)
Linkage analysis of susceptibility to hyperoxia - Nrf2 is a candidate gene
HY Cho et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2002)
Oxidant stress mechanism of homocysteine potentiating Con A-induced proliferation in murine splenic T lymphocytes
Q Zhang et al.
CARDIOVASCULAR RESEARCH (2002)
Modulatory effects of garlic extracts on proliferation of T-lymphocytes in vitro stimulated with concanavalin A
M Colic et al.
PHYTOMEDICINE (2002)
Inhibition of activated/memory (CD45RO+) T cells by oxidative stress associated with block of NF-κB activation
KJ Malmberg et al.
JOURNAL OF IMMUNOLOGY (2001)
Heme oxygenase-1 plays an important protective role in experimental autoimmune encephalomyelitis
YR Liu et al.
NEUROREPORT (2001)
Innate immune mechanisms in the pathogenesis of systemic lupus erythematosus (SLE)
H de la Fuente et al.
IMMUNOLOGY LETTERS (2001)
Gender differences in autoimmunity: molecular basis for estrogen effects in systemic lupus erythematosus
V Rider et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2001)
Inhibitory effect of DCDC on lipopolysaccharide-induced nitric oxide synthesis in RAW 264.7 cells
YC Huang et al.
LIFE SCIENCES (2001)
Heme oxygenase-1 and NADPH cytochrome P450 reductase expression in experimental allergic encephalomyelitis: An expanded view of the stress response
MR Emerson et al.
JOURNAL OF NEUROCHEMISTRY (2000)
Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1
D Jaarsma et al.
NEUROBIOLOGY OF DISEASE (2000)
MAPK/ERK signaling in activated T cells inhibits CD95/Fas-mediated apoptosis downstream of DISC assembly
TH Holmström et al.
EMBO JOURNAL (2000)
Lineage-specific telomere shortening and unaltered capacity for telomerase expression in human T and B lymphocytes with age
NH Son et al.
JOURNAL OF IMMUNOLOGY (2000)
JNK is required for effector T-cell function but not for T-cell activation
C Dong et al.
NATURE (2000)
Endogenous oxygen radicals modulate protein tyrosine phosphorylation and JNK-1 activation in lectin-stimulated thymocytes
G Pani et al.
BIOCHEMICAL JOURNAL (2000)
Displacement of linker for activation of T cells from the plasma membrane due to redox balance alterations results in hyporesponsiveness of synovial fluid T lymphocytes in rheumatoid arthritis
SI Gringhuis et al.
JOURNAL OF IMMUNOLOGY (2000)
Expression of thioredoxin in granulomas of sarcoidosis: possible role in the development of T lymphocyte activation
T Koura et al.
THORAX (2000)