期刊
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
卷 93, 期 1, 页码 7-10出版社
AMER SOC TROP MED & HYGIENE
DOI: 10.4269/ajtmh.14-0543
关键词
-
资金
- Fondo Nacional de Ciencia y Ttecnologia (FONACIT) [S1-2002000338]
- Organizacion Panamericana de la Salud (OPS)
- Defense Threat Reduction Agency under Lawrence Livermore National Laboratory [DTRA10027IA-2359-BASIC]
- James W. McLaughlin Endowment Fund
Several species of alphaviruses have been previously described in the Americas, some of which are associated with encephalitis and others are associated with arthralgia. Venezuelan equine encephalitis virus (VEEV) and eastern equine encephalitis virus (EEEV) are endemic to Venezuela, with the former being responsible for major outbreaks of severe and often fatal disease in animals and humans. The aim of this study was to analyze the genetic diversity of Venezuelan alphaviruses isolated during two decades (1973-1999) of surveillance in northern Venezuela. Phylogenetic analysis indicated the circulation of a VEEV subtype LAB strain 8 years after the last reported outbreak. Thirteen strains within two subclades of South American lineage III of EEEV were also found in Venezuela. Considerable genetic variability was observed among Venezuelan Una virus strains, which were widely distributed among the clades. The first Venezuelan Mayaro sequence was also characterized.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据