期刊
MULTIPLE SCLEROSIS JOURNAL
卷 11, 期 5, 页码 617-621出版社
SAGE PUBLICATIONS LTD
DOI: 10.1191/1352458505ms1200cr
关键词
Devic's; hypothalamus; multiple sclerosis; neuromyelitis optica; spino-optic
We describe two cases of neuromyelitis optica (NMO) with clinical and radiographically confirmed features of hypothalamic involvement, in the absence of other parenchymal brain lesions. Their course is otherwise typical of Devic's form of NMO. A review of the literature identifies additional cases of NMO in which clinical features attributable to under-recognized dysfunction of the hypothalamic - pituitary axis were present. We propose that the currently accepted criteria for the diagnosis of NMO could be revisited to recognize the possibility of lesions developing within hypothalamic structures.
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