相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Human MRCKα is regulated by cellular iron levels and interferes with transferrin iron uptake
Radek Cmejla et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Ferrochelatase forms an oligomeric complex with mitoferrin-1 and Abcb10 for erythroid heme biosynthesis
Wen Chen et al.
BLOOD (2010)
Mitochondrial Iron Metabolism and Its Role in Neurodegeneration
Maxx P. Horowitz et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Glutaredoxin 5 deficiency causes sideroblastic anemia by specifically impairing heme biosynthesis and depleting cytosolic iron in human erythroblasts
Hong Ye et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol
Des R. Richardson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Iron-sulfur proteins in health and disease
Alex Sheftel et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2010)
The role of iron in mitochondrial function
Sonia Levi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2009)
Ferritins: A family of molecules for iron storage, antioxidation and more
Paolo Arosio et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2009)
Hepcidin, the hormone of iron metabolism, is bound specifically to α-2-macroglobulin in blood
Gabriela Peslova et al.
BLOOD (2009)
Clinical manifestation and a new ISCU mutation in ironsulphur cluster deficiency myopathy
Gittan Kollberg et al.
BRAIN (2009)
Function and biogenesis of iron-sulphur proteins
Roland Lill
NATURE (2009)
Mutations in mitochondrial carrier family gene SLC25A38 cause nonsyndromic autosomal recessive congenital sideroblastic anemia
Duane L. Guernsey et al.
NATURE GENETICS (2009)
Bacterial frataxin CyaY is the gatekeeper of iron-sulfur cluster formation catalyzed by IscS
Salvatore Adinolfi et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
ABCs of erythroid mitochondrial iron uptake
Nancy C. Andrews
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Elucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutant
Michael Li-Hsuan Huang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria
Wen Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
An E3 Ligase Possessing an Iron-Responsive Hemerythrin Domain Is a Regulator of Iron Homeostasis
Ameen A. Salahudeen et al.
SCIENCE (2009)
Control of Iron Homeostasis by an Iron-Regulated Ubiquitin Ligase
Ajay A. Vashisht et al.
SCIENCE (2009)
Splice mutation in the iron-sulfur cluster scaffold protein ISCU causes myopathy with exercise intolerance
Fanny Mochel et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2008)
Systemic Iron Homeostasis and the Iron-Responsive Element/Iron-Regulatory Protein (IRE/IRP) Regulatory Network
Martina U. Muckenthaler et al.
Annual Review of Nutrition (2008)
Myopathy with lactic acidosis is linked to chromosome 12q23.3-24.11 and caused by an intron mutation in the ISCU gene resulting in a splicing defect
Angelica Olsson et al.
HUMAN MOLECULAR GENETICS (2008)
Binding of yeast frataxin to the scaffold for Fe-S cluster biogenesis, Isu
Tao Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Mitochondrial Dysfunction in Neurodegenerative Diseases
Anthony H. V. Schapira
NEUROCHEMICAL RESEARCH (2008)
The MCK mouse heart model of Friedreich's ataxia: Alterations in iron-regulated proteins and cardiac hypertrophy are limited by iron chelation
Megan Whitnall et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Iron-sulfur cluster biogenesis and human disease
Tracey A. Rouault et al.
TRENDS IN GENETICS (2008)
A π-helix switch selective for porphyrin deprotonation and product release in human ferrochelatase
Amy E. Medlock et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Mitochondrial ferritin expression in adult mouse tissues
Paolo Santambrogio et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2007)
Non-transferrin-bound iron reaches mitochondria by a chelator-inaccessible mechanism: biological and clinical implications
Maya Shvartsman et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2007)
Excess capacity of the iron regulatory protein system
Wei Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
The human counterpart of zebrafish shiraz shows sideroblastic-like microcytic anemia and iron overload
Clara Camaschella et al.
BLOOD (2007)
Selective iron chelation in Friedreich ataxia:: biologic and clinical implications
Nathalie Boddaert et al.
BLOOD (2007)
Direct interorganellar transfer of iron from endosome to mitochondrion
Alex D. Sheftel et al.
BLOOD (2007)
Molecular control of iron transport
Tomas Ganz
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2007)
Iron uptake and metabolism in the new millennium
Louise L. Dunn et al.
TRENDS IN CELL BIOLOGY (2007)
Human frataxin:: iron and ferrochelatase binding surface
Krisztina Z. Bencze et al.
CHEMICAL COMMUNICATIONS (2007)
Suppression of hepcidin during anemia requires erythropoietic activity
Mihwa Pak et al.
BLOOD (2006)
p16INK4a induces an age-dependent decline in islet regenerative potential
Janakiraman Krishnamurthy et al.
NATURE (2006)
Monomeric yeast frataxin is an iron-binding protein
Jeremy D. Cook et al.
BIOCHEMISTRY (2006)
The anemia of haemoglobin-deficit (hbd/hbd) mice is caused by a defect in transferrin cycling
An-Sheng Zhang et al.
EXPERIMENTAL HEMATOLOGY (2006)
A splice-supporting intronic mutation in the last bp position of a cryptic exon within intron 6 of the CYBB gene induces its incorporation into the mRNA causing chronic granulomatous disease (CGD)
A Rump et al.
GENE (2006)
The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron-sulfur cluster biogenesis
C Pondarré et al.
HUMAN MOLECULAR GENETICS (2006)
A novel iron responsive element in the 3′UTR of human MRCKα
R Cmejla et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Mitoferrin is essential for erythroid iron assimilation
GC Shaw et al.
NATURE (2006)
Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis
WH Tong et al.
CELL METABOLISM (2006)
Frataxin deficiency alters heme pathway transcripts and decreases mitochondrial heme metabolites in mammalian cells
RA Schoenfeld et al.
HUMAN MOLECULAR GENETICS (2005)
Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells
RS Ohgami et al.
NATURE GENETICS (2005)
A mutation in Sec15l1 causes anemia in hemoglobin deficit (hbd) mice
JE Lim et al.
NATURE GENETICS (2005)
Increased duodenal iron uptake and transfer in a rat model of chronic hypoxia is accompanied by reduced hepcidin expression
PS Leung et al.
GUT (2005)
Altered body iron distribution and rmicrocytosis in mice deficient in iron regulatory protein 2 (IRP2)
B Galy et al.
BLOOD (2005)
Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis
RA Wingert et al.
NATURE (2005)
A mouse model of juvenile hemochromatosis
FW Huang et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2
SS Cooperman et al.
BLOOD (2005)
Peroxisome proliferator-activated receptor γ-independent ablation of cyclin D1 by thiazolidinediones and their derivatives in breast cancer cells
JW Huang et al.
MOLECULAR PHARMACOLOGY (2005)
Overexpression of mitochondrial ferritin causes cytosolic iron depletion and changes cellular iron homeostasis
GJ Nie et al.
BLOOD (2005)
Iron trafficking in the mitochondrion: novel pathways revealed by disease
I Napier et al.
BLOOD (2005)
The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis
A Donovan et al.
CELL METABOLISM (2005)
Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia
S Rivera et al.
BLOOD (2005)
Regulation of hepcidin transcription by interleukin-1 and interleukin-6
P Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Intracellular kinetics of iron in reticulocytes: evidence for endosome involvement in iron targeting to mitochondria
AS Zhang et al.
BLOOD (2005)
Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin
MD Knutson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Supramolecular assemblies of human frataxin are formed via subunit-subunit interactions mediated by a non-conserved amino-terminal region
HA O'Neill et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Assembly of human frataxin is a mechanism for detoxifying redox-active iron
HA O'Neill et al.
BIOCHEMISTRY (2005)
Crystal structure of protoporphyrinogen IX oxidase: a key enzyme in haem and chlorophyll biosynthesis
M Koch et al.
EMBO JOURNAL (2004)
Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis
EG Meyron-Holtz et al.
EMBO JOURNAL (2004)
The expression of human mitochondrial ferritin rescues respiratory function infrataxin-deficient yeast
A Campanella et al.
HUMAN MOLECULAR GENETICS (2004)
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
E Nemeth et al.
SCIENCE (2004)
Frataxin acts as an iron chaperone protein to modulate mitochondrial aconitase activity
AL Bulteau et al.
SCIENCE (2004)
The heme synthesis defect of mutants impaired in mitochondrial iron-sulfur protein biogenesis is caused by reversible inhibition of ferrochelatase
H Lange et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Frataxin-mediated iron delivery to ferrochelatase in the final step of heme biosynthesis
T Yoon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Iron-induced oligomerization of yeast frataxin homologue Yfh1 is dispensable in vivo
K Aloria et al.
EMBO REPORTS (2004)
Targeting, import, and dimerization of a mammalian mitochondrial ATP binding cassette (ABC) transporter, ABCB10 (ABC-me)
SA Graf et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
E Nemeth et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
A specific role of the yeast mitochondrial carriers Mrs3/4p in mitochondrial iron acquisition under iron-limiting conditions
U Mühlenhoff et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Subcellular compartmentalization of human Nfu, an iron-sulfur cluster scaffold protein, and its ability to assemble a [4Fe-4S] cluster
WH Tong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Yeast frataxin sequentially chaperones and stores iron by coupling protein assembly with iron oxidation
S Park et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Iron-sulfur cluster biosynthesis. Characterization of frataxin as an iron donor for assembly of [2Fe-2S] clusters in ISU-type proteins
T Yoon et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Involvement of ABC7 in the biosynthesis of heme in erythroid cells: interaction of ABC7 with ferrochelatase
S Taketani et al.
BLOOD (2003)
Iron use for haeme synthesis is under control of the yeast frataxin homologue (Yfh1)
E Lesuisse et al.
HUMAN MOLECULAR GENETICS (2003)
Formation of iron-sulfur clusters in bacteria: an emerging field in bioinorganic chemistry
J Frazzon et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2003)
Mitochondrial ferritin expression in erythroid cells from patients with sideroblastic anemia
M Cazzola et al.
BLOOD (2003)
Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis
KR Bridle et al.
LANCET (2003)
Iron loading and erythrophagocytosis increase ferroportin 1 (FPN1) expression in J774 macrophages
MD Knutson et al.
BLOOD (2003)
Friedreich's Ataxia: Disease mechanisms, antioxidant and coenzyme Q(10) therapy
JM Cooper et al.
BIOFACTORS (2003)
Biogenesis of iron-sulfur proteins in eukaryotes: components, mechanism and pathology
J Gerber et al.
MITOCHONDRION (2002)
Mitochondrial ferritin: A new player in iron metabolism
J Drysdale et al.
BLOOD CELLS MOLECULES AND DISEASES (2002)
Decreased liver hepcidin expression in the Hfe knockout mouse
KA Ahmad et al.
BLOOD CELLS MOLECULES AND DISEASES (2002)
The labile iron pool: Characterization, measurement, and participation in cellular processes
O Kakhlon et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
The ferroxidase activity of yeast frataxin
S Park et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
A structural approach to understanding the iron-binding properties of phylogenetically different frataxins
S Adinolfi et al.
HUMAN MOLECULAR GENETICS (2002)
Deletion of the mitochondrial carrier genes MRS3 and MRS4 suppresses mitochondrial iron accumulation in a yeast frataxin-deficient strain
F Foury et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Human mitochondrial ferritin expressed in HeLa cells incorporates iron and affects cellular iron metabolism
B Corsi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Erythroid differentiation and protoporphyrin IX down-regulate frataxin expression in Friend cells: characterization of frataxin expression compared to molecules involved in iron metabolism and hemoglobinization
EM Becker et al.
BLOOD (2002)
Molecular bases of cellular iron toxicity
JW Eaton et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
Grx5 is a mitochondrial glutaredoxin required for the activity of iron/sulfur enzymes
MT Rodríguez-Manzaneque et al.
MOLECULAR BIOLOGY OF THE CELL (2002)
Assembly and iron-binding properties of human frataxin, the protein deficient in Friedreich ataxia
P Cavadini et al.
HUMAN MOLECULAR GENETICS (2002)
Iron-dependent regulation of the divalent metal ion transporter
H Gunshin et al.
FEBS LETTERS (2001)
X-linked cerebellar ataxia and sideroblastic anaemia associated with a missense mutation in the ABC7 gene predicting V411L
A Maguire et al.
BRITISH JOURNAL OF HAEMATOLOGY (2001)
Sticky DNA, a self-associated complex formed at long GAA•TTC repeats in intron 1 of the frataxin gene, inhibits transcriptions
N Sakamoto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
A human mitochondrial ferritin encoded by an intronless gene
S Levi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Hepcidin, a urinary antimicrobial peptide synthesized in the liver
CH Park et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits
H Puccio et al.
NATURE GENETICS (2001)
Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice
T LaVaute et al.
NATURE GENETICS (2001)
Frataxin: its role in iron metabolism and the pathogenesis of Friedreich's ataxia
E Becker et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2001)
Distinct iron-sulfur cluster assembly complexes exist in the cytosol and mitochondria of human cells
WH Tong et al.
EMBO JOURNAL (2000)
Iron-dependent self assembly of recombinant yeast frataxin: Implications for Friedreich ataxia
J Adamec et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2000)
Towards a structural understanding of Friedreich's ataxia: the solution structure of frataxin
G Musco et al.
STRUCTURE (2000)
MTABC3, a novel mitochondrial ATP-binding cassette protein involved in iron homeostasis
N Mitsuhashi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
ABC-me: a novel mitochondrial transporter induced by GATA-1 during erythroid differentiation
OS Shirihai et al.
EMBO JOURNAL (2000)
Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter
A Donovan et al.
NATURE (2000)
A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation
AT McKie et al.
MOLECULAR CELL (2000)