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注意:仅列出部分参考文献,下载原文获取全部文献信息。Polymerases in Nonhomologous End Joining: Building a Bridge over Broken Chromosomes
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Ying Huang et al.
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Formation of clustered DNA damage after high-LET irradiation: A review
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Cryo-EM structure of the DNA-Dependent protein kinase catalytic subunit at subnanometer resolution reveals α helices and insight into DNA binding
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Regulation of DNA double-strand break repair pathway choice
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Flexibility in the order of action and in the enzymology of the nuclease, polymerases, and ligase of vertebrate nonhomologous DNA end joining: relevance to cancer, aging, and the immune system
Michael R. Lieber et al.
CELL RESEARCH (2008)
Structure of a NHEJ polymerase-mediated DNA synaptic complex
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Human polynucleotide kinase participates in repair of DNA double-strand breaks by nonhomologous end joining but not homologous recombination
Feridoun Karimi-Busheri et al.
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trans Autophosphorylation at DNA-dependent protein kinase's two major autophosphorylation site clusters facilitates end processing but not end joining
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Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks
Naoya Uematsu et al.
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Loading of the nonhomologous end joining factor, Ku, on protein-occluded DNA ends
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JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps
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Processing of 3′-phosphoglycolate-terminated DNA double strand breaks by artemis nuclease
Lawrence F. Povirk et al.
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Gaps and forks in DNA replication: Rediscovering old models
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Distinct mechanisms of nonhomologous end joining in the repair of site-directed chromosomal breaks with noncomplementary and complementary ends
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Interplay between Ku, artemis, and the DNA-dependent protein kinase catalytic subunit at DNA ends
Jerome Drouet et al.
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DNA-PK autophosphorylation facilitates Artemis endonuclease activity
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Artemis phosphorylated by DNA-dependent protein kinase associates preferentially with discrete regions of chromatin
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WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing
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Analysis of DNA-dependent protein kinase-mediated DNA end joining by two-photon fluorescence cross-correlation spectroscopy
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XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining
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Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly
D Buck et al.
CELL (2006)
Terminal DNA structure and ATP influence binding parameters of the DNA-dependent protein kinase at an early step prior to DNA synapsis
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Segregation of genomes in polyploid tumour cells following mitotic catastrophe
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CELL BIOLOGY INTERNATIONAL (2005)
Autophosphorylation of DNA-dependent protein kinase regulates DNA end processing and may also alter double-strand break repair pathway choice
XP Cui et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
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YM Ma et al.
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P Douglas et al.
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Processing of DNA for nonhomologous end-joining by cell-free extract
J Budman et al.
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Differential activation of DNA-PK based on DNA strand orientation and sequence bias
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PI 3-kinase related kinases: 'big' players in stress-induced signaling pathways
RT Abraham
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Impact of the KU80 pathway on NHEJ-induced genome rearrangements in mammalian cells
J Guirouilh-Barbat et al.
MOLECULAR CELL (2004)
Functional and biochemical dissection of the structure-specific nuclease ARTEMIS
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EMBO JOURNAL (2004)
Ku stimulation of DNA ligase IV-dependent ligation requires inward movement along the DNA molecule
B Kysela et al.
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Defective DNA repair and increased genomic instability in artemis-deficient murine cells
S Rooney et al.
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Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase
P Douglas et al.
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The DNA-dependent protein kinase interacts with DNA to form a protein-DNA complex that is disrupted by phosphorylation
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Association of DNA polymerase μ (pol μ) with Ku and ligase IV:: Role for pol μ in end-joining double-strand break repair
KN Mahajan et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Synapsis of DNA ends by DNA-dependent protein kinase
LG DeFazio et al.
EMBO JOURNAL (2002)
Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination
YM Ma et al.
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DNA length-dependent cooperative interactions in the binding of Ku to DNA
YM Ma et al.
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CF Chiu et al.
MUTATION RESEARCH-DNA REPAIR (2001)
Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair
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Cisplatin-DNA adducts inhibit translocation of the Ku subunits of DNA-PK
JJ Turchi et al.
NUCLEIC ACIDS RESEARCH (2000)
Activation of DNA-dependent protein kinase by single-stranded DNA ends
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JOURNAL OF BIOLOGICAL CHEMISTRY (2000)