期刊
ANTIOXIDANTS & REDOX SIGNALING
卷 14, 期 2, 页码 241-259出版社
MARY ANN LIEBERT, INC
DOI: 10.1089/ars.2010.3250
关键词
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资金
- National Institutes of Health [R37 AG016694, RO1 AG35328, P20 RR015578]
- Ellison Medical Foundation [AG-SS-1912-07]
- NATIONAL CENTER FOR RESEARCH RESOURCES [P20RR015578] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON AGING [R37AG016694, R01AG035328] Funding Source: NIH RePORTER
Organismal aging and longevity are influenced by many complex interacting factors. Epigenetics has recently emerged as another possible determinant of aging. Here, we review some of the epigenetic pathways that contribute to cellular senescence and age-associated phenotypes. Strategies aimed to reverse age-linked epigenetic alterations may lead to the development of new therapeutic interventions to delay or alleviate some of the most debilitating age-associated diseases. Antioxid. Redox Signal. 14, 241-259.
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