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The NAD(P)H oxidase homolog Nox4 modulates insulin-stimulated generation of H2O2 and plays an integral role in insulin signal transduction
K Mahadev et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Structural and functional characterization of the two human ThOX/Duox genes and their 5′-flanking regions
J Pachucki et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2004)
Assessment of renal functional phenotype in mice lacking gp91PHOX subunit of NAD(P)H oxidase
MZ Haque et al.
HYPERTENSION (2004)
Nox3 regulation by NOXO1, p47phox, and p67phox
GJ Cheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species-dependent endothelial migration and proliferation
M Yamaoka-Tojo et al.
CIRCULATION RESEARCH (2004)
Insights into the redox control of blood coagulation:: Role of vascular NADPH oxidase-derived reactive oxygen species in the thrombogenic cycle
O Herkert et al.
ANTIOXIDANTS & REDOX SIGNALING (2004)
Rac regulates thrombin-induced tissue factor expression in pulmonary artery smooth muscle cells involving the nuclear factor-κB pathway
T Djordjevic et al.
ANTIOXIDANTS & REDOX SIGNALING (2004)
Targeting of the dual oxidase 2 N-terminal region to the plasma membrane
S Morand et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Reactive oxygen species mediate met receptor transactivation by G protein-coupled receptors and the epidermal growth factor receptor in human carcinoma cells
OM Fischer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
NAD(P)H oxidase Nox-4 mediates 7-ketocholesterol-induced endoplasmic reticulum stress and apoptosis in human aortic smooth muscle cells
E Pedruzzi et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors
J Kwon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
The NADPH oxidase of professional phagocytes - prototype of the NOX electron transport chain systems
AR Cross et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2004)
Ligand-dependent autophosphorylation of the insulin receptor is positively regulated by Gi-proteins
J Kreuzer et al.
BIOCHEMICAL JOURNAL (2004)
Hijacking epidermal growth factor receptors by angiotensin II: new possibilities for understanding and treating cardiac hypertrophy
NJ Smith et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2004)
Role of p22phox in angiotensin II and platelet-derived growth factor AA induced activator protein I activation in vascular smooth muscle cells
C Viedt et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2004)
Sequential activation of phosphatidylinositol 3-kinase, βPix, Rac1, and Nox1 in growth factor-induced production of H2O2
HS Park et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Hydrogen peroxide signaling through tumor necrosis factor receptor 1 leads to selective activation of c-Jun N-terminal kinase
C Pantano et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
G protein βγ subunits stimulate p114RhoGEF, a guanine nucleotide exchange factor for RhoA and Rac1 -: Regulation of cell shape and reactive oxygen species production
JX Niu et al.
CIRCULATION RESEARCH (2003)
TNF-α induces phosphorylation of p47phox in human neutrophils:: Partial phosphorylation of p47phox is a common event of priming of human neutrophils by TNF-α and granulocyte-macrophage colony-stimulating factor
C Dewas et al.
JOURNAL OF IMMUNOLOGY (2003)
Vascular endothelial growth factor causes translocation of p47phox to membrane ruffles through WAVE1
RF Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Cellular regulation by hydrogen peroxide
SG Rhee et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2003)
Nox4 mediates angiotensin II-induced activation of Akt/protein kinase B in mesangial cells
Y Gorin et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2003)
Novel human homologues of p47phox and p67phox participate in activation of superoxide-producing NADPH oxidases
R Takeya et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
c-Src induces phosphorylation and translocation of p47phox - Role in superoxide generation by angiotensin II in human vascular smooth muscle cells
RM Touyz et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2003)
Molecular basis of phosphorylation-induced activation of the NADPH oxidase
Y Groemping et al.
CELL (2003)
Mechanism of endothelial cell NADPH oxidase activation by angiotensin II -: Role of the p47Phox subunit
JM Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Effect of iodide on nicotinamide adenine dinucleotide phosphate oxidase activity and Duox2 protein expression in isolated porcine thyroid follicles
S Morand et al.
ENDOCRINOLOGY (2003)
Identification of a novel protein, PDIP38, that interacts with the p50 subunit of DNA polymerase δ and proliferating cell nuclear antigen
L Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Two novel proteins activate superoxide generation by the NADPH oxidase NOX1
B Bánfi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The molecular basis for adhesion-mediated suppression of reactive oxygen species generation by human neutrophils
TM Zhao et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Regulation of neutrophil function by Rac GTPases
MC Dinauer
CURRENT OPINION IN HEMATOLOGY (2003)
Tumor necrosis factor signaling
H Wajant et al.
CELL DEATH AND DIFFERENTIATION (2003)
The adaptor protein p40phox as a positive regulator of the superoxide-producing phagocyte oxidase
F Kuribayashi et al.
EMBO JOURNAL (2002)
Phosphorylation of p85 βPIX, a Rac/Cdc42-specific guanine nucleotide exchange factor, via the Ras/ERK/PAK2 pathway is required for basic fibroblast growth factor-induced neurite outgrowth
EY Shin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Proteins of the PDI family: Unpredicted non-ER locations and functions
C Turano et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2002)
Platelet-derived growth factor activates production of reactive oxygen species by NAD(P)H-oxidase in smooth muscle cells through Gi1,2
J Kreuzer et al.
FASEB JOURNAL (2002)
Angiotensin II stimulation of NAD(P)H oxidase activity - Upstream mediators
PN Seshiah et al.
CIRCULATION RESEARCH (2002)
Recent advances in angiotensin II signaling
RM Toyz et al.
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH (2002)
Cellular regulation of RGS proteins: Modulators and integrators of G protein signaling
S Hollinger et al.
PHARMACOLOGICAL REVIEWS (2002)
Inactivating mutations in the gene for thyroid oxidase 2 (THOX2) and congenital hypothyroidism
JC Moreno et al.
NEW ENGLAND JOURNAL OF MEDICINE (2002)
VAV proteins as signal integrators for multi-subunit immune-recognition receptors
M Turner et al.
NATURE REVIEWS IMMUNOLOGY (2002)
Expression of a functionally active gp91phox-containing neutrophil-type NAD(P)H oxidase in smooth muscle cells from human resistance arteries - Regulation by angiotensin II
RM Touyz et al.
CIRCULATION RESEARCH (2002)
The vascular NADPH oxidase subunit p47phox is involved in redox-mediated gene expression
RP Brandes et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
Rac activation induces NADPH oxidase activity in transgenic COSphox cells, and the level of superoxide production is exchange factor-dependent
MO Price et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
PKCζ regulates TNF-α-induced activation of NADPH oxidase in endothelial cells
RS Frey et al.
CIRCULATION RESEARCH (2002)
NADPH oxidase mediates tissue factor-dependent surface procoagulant activity by thrombin in human vascular smooth muscle cells
O Herkert et al.
CIRCULATION (2002)
AT1 receptor mutant lacking heterotrimeric G protein coupling activates the Src-Ras-ERK pathway without nuclear translocation of ERKs
K Seta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Characterization of ThOX proteins as components of the thyroid H2O2-generating system
X De Deken et al.
EXPERIMENTAL CELL RESEARCH (2002)
Role of neutrophil NADPH oxidase in the mechanism of tumor necrosis factor-α-induced NF-κB activation and intercellular adhesion molecule-1 expression in endothelial cells
J Fan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The endothelial receptor tyrosine kinase Tie1 activates phosphatidylinositol 3-kinase and Akt to inhibit apoptosis
CD Kontos et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Hydrogen peroxide generated during cellular insulin stimulation is integral to activation of the distal insulin signaling cascade in 3T3-L1 adipocytes
K Mahadev et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Insulin signalling and the regulation of glucose and lipid metabolism
AR Saltiel et al.
NATURE (2001)
A Ca2+-activated NADPH oxidase in testis, spleen, and lymph nodes
B Bánfi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Thrombin causes vascular endothelial growth factor expression in vascular smooth muscle cells -: Role of reactive oxygen species
S Bassus et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2001)
Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells role of the p22phox-containing NADPH oxidase
A Görlach et al.
CIRCULATION RESEARCH (2001)
Insulin-stimulated hydrogen peroxide reversibly inhibits protein-tyrosine phosphatase 1B in vivo and enhances the early insulin action cascade
K Mahadev et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Homologs of gp91phox:: cloning and tissue expression of Nox3, Nox4, and Nox5
GJ Cheng et al.
GENE (2001)
Novel gp91phox homologues in vascular smooth muscle cells -: Nox1 mediates angiotensin II-induced superoxide formation and redox-sensitive signaling pathways
B Lassègue et al.
CIRCULATION RESEARCH (2001)
Epidermal growth factor receptor transactivation by angiotensin II requires reactive oxygen species in vascular smooth muscle cells
M Ushio-Fukai et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2001)
Molecular basis for Rac2 regulation of phagocyte NADPH oxidase
BA Diebold et al.
NATURE IMMUNOLOGY (2001)
Novel homologs of gp91phox
JD Lambeth et al.
TRENDS IN BIOCHEMICAL SCIENCES (2000)
Phosphorylation of p22phox is mediated by phospholipase D-dependent and -independent mechanisms -: Correlation of NADPH oxidase activity and p22phox phosphorylation
DS Regier et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family
X De Deken et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
A gp91phox containing NADPH oxidase selectively expressed in endothelial cells is a major source of oxygen radical generation in the arterial wall
A Görlach et al.
CIRCULATION RESEARCH (2000)
Platelet-derived growth factor-induced H2O2 production requires the activation of phosphatidylinositol 3-kinase
YS Bae et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
NAD(P)H oxidase - Role in cardiovascular biology and disease
KK Griendling et al.
CIRCULATION RESEARCH (2000)
The trimeric GTP-binding protein (Gq/G11) α subunit is required for insulin-stimulated GLUT4 translocation in 3T3L1 adipocytes
M Kanzaki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)