相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Neurodegenerative lysosomal disorders - A continuum from development to late age
Ralph A. Nixon et al.
AUTOPHAGY (2008)
Alzheimer Disease and the Role of Free Radicals in the Pathogenesis of the Disease
George Perry et al.
CNS & Neurological Disorders-Drug Targets (2008)
Autophagic-lysosomal perturbation enhances tau aggregation in transfectants with induced wild-type tau expression
Tadanori Hamano et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2008)
The autophagy-lysosomal degradation pathway: role in neurodegenerative disease and therapy
John J. Shacka et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2008)
Zinc and 4-hydroxy-2-nonenal mediate lysosomal membrane permeabilization induced by H2O2 in cultured hippocampal neurons
Jung Jin Hwang et al.
JOURNAL OF NEUROSCIENCE (2008)
Chloroquine-induced nitric oxide increase and cell death is dependent on cellular GSH depletion in A172 human glioblastoma cells
Byung Chul Park et al.
TOXICOLOGY LETTERS (2008)
Autophagy, amyloidogenesis and Alzheimer disease
Ralph A. Nixon
JOURNAL OF CELL SCIENCE (2007)
Zaprinast inhibits hydrogen peroxide-induced lysosomal destabilization and cell death in astrocytes
Jae-Hyuck Choi et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2007)
Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins
Nathan W. Werneburg et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Cell cycle-dependent induction of autophagy, mitophagy and reticulophagy
Ezgi Tasdemir et al.
CELL CYCLE (2007)
Involvement of lysosomal storage-induced p38 MAP kinase activation in the overproduction of nitric oxide by microglia in cathepsin D-deficient mice
Ryo Yamasaki et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2007)
Neuronal apoptosis in neurodegeneration
Masahiro Okouchi et al.
ANTIOXIDANTS & REDOX SIGNALING (2007)
Selective degradation of mitochondria by mitophagy
Insil Kim et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2007)
Autophagy, ageing and apoptosis: The role of oxidative stress and lysosomal iron
Tino Kurz et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2007)
Autophagocytosis of mitochondria is prominent in Alzheimer disease
Paula I. Moretra et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2007)
Altered regulation of phosphatidylinositol 3-kinase signaling in cathepsin D-deficient brain
Ken C. Walls et al.
AUTOPHAGY (2007)
Selective autophagy of the endoplasmic reticulum
Sebastian Bernales et al.
AUTOPHAGY (2007)
Cathepsin D-Bax death pathway in oxidative stressed neuroblastoma cells
Roberta Castino et al.
FREE RADICAL BIOLOGY AND MEDICINE (2007)
Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
Ruth Scherz-Shouval et al.
EMBO JOURNAL (2007)
Cathepsin D deficiency induces persistent neurodegeneration in the absence of Bax-dependent apoptosis
John J. Shacka et al.
JOURNAL OF NEUROSCIENCE (2007)
Bioenergetics and the formation of mitochondrial reactive oxygen species
Vera Adam-Vizi et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2006)
The lysosomal-mitochondrial axis theory of postmitotic aging and cell death
Alexei Terman et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2006)
Antiamyloidogenic and neuroprotective functions of cathepsin B: implications for Alzheimer's disease
Sarah Mueller-Steiner et al.
NEURON (2006)
Two distinct signaling pathways regulate peroxynitrite-induced apoptosis in PC12 cells
J. J. Shacka et al.
CELL DEATH AND DIFFERENTIATION (2006)
Hypochlorous acid induces apoptosis of cultured cortical neurons through activation of calpains and rupture of lysosomes
Yann Wan Yap et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Ceramide is the key mediator of oxidative stress-induced apoptosis in retinal photoreceptor cells
Nuria Sanvicens et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Release of iron from ferritin requires lysosomal activity
Theodros Z. Kidane et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)
New insights on the use of desipramine as an inhibitor for acid ceramidase
Saeed Elojeimy et al.
FEBS LETTERS (2006)
Autophagy, bafilomycin and cell death - The A-B-Cs of plecomacrolide-induced neuroprotection
JJ Shacka et al.
AUTOPHAGY (2006)
Cytosolic acidification and lysosomal alkalinization during TNF-α induced apoptosis in U937 cells
C Nilsson et al.
APOPTOSIS (2006)
Intralysosomal iron chelation protects against oxidative stress-induced cellular damage
Tino Kurz et al.
FEBS JOURNAL (2006)
Cathepsin D deficiency is associated with a human neurodegenerative disorder
Robert Steinfeld et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2006)
Different conformations of amyloid β induce neurotoxicity by distinct mechanisms in human cortical neurons
Atul Deshpande et al.
JOURNAL OF NEUROSCIENCE (2006)
Bafilomycin A1 inhibits chloroquine-induced death of cerebellar granule neurons
JJ Shacka et al.
MOLECULAR PHARMACOLOGY (2006)
A mutation in the cathepsin D gene (CTSD) in American Bulldogs with neuronal ceroid lipofuscinosis
T Awano et al.
MOLECULAR GENETICS AND METABOLISM (2006)
Autophagy of amyloid beta-protein in differentiated neuroblastoma cells exposed to oxidative stress
L Zheng et al.
NEUROSCIENCE LETTERS (2006)
Metallothionein protects against oxidative stress-induced lysosomal destabilization
SK Baird et al.
BIOCHEMICAL JOURNAL (2006)
Cathepsin D deficiency underlies congenital human neuronal ceroid-lipofuscinosis
Eija Siintola et al.
BRAIN (2006)
Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease)
M Koike et al.
AMERICAN JOURNAL OF PATHOLOGY (2005)
Cellular responses to protein accumulation involve autophagy and lysosomal enzyme activation
D Butler et al.
REJUVENATION RESEARCH (2005)
Redundant cell death mechanisms as relics and backups
P Golstein et al.
CELL DEATH AND DIFFERENTIATION (2005)
Macroautophagy -: a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease
WH Yu et al.
JOURNAL OF CELL BIOLOGY (2005)
Chloroquine-mediated radiosensitization is due to the destabilization of the lysosomal membrane and subsequent induction of cell death by necrosis
H Zhao et al.
RADIATION RESEARCH (2005)
Disruptive effect of chloroquine on lysosomes in cultured rat hepatocytes
A Michihara et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2005)
Role of the autophagic-lysosomal system on low potassium-induced apoptosis in cultured cerebellar granule cells
N Canu et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Extensive involvement of autophagy in Alzheimer disease: An immuno-electron microscopy study
RA Nixon et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2005)
Cathepsin D links TNF-induced acid sphingomyelinase to Bid-mediated caspase-9 and-3 activation
M Heinrich et al.
CELL DEATH AND DIFFERENTIATION (2004)
Lysosomes in cell death
ME Guicciardi et al.
ONCOGENE (2004)
Ferriprotoporphyrin IX, phospholipids, and the antimalarial actions of quinoline drugs
CD Fitch
LIFE SCIENCES (2004)
Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of bid by multiple papain-like lysosomal cathepsins
T Cirman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Brain iron deposition and the free radical-mitochondrial theory of ageing
HM Schipper
AGEING RESEARCH REVIEWS (2004)
Examination of the mechanism(s) involved in doxorubicin-mediated iron accumulation in ferritin: Studies using metabolic inhibitors, protein synthesis inhibitors, and lysosomotropic agents
JC Kwok et al.
MOLECULAR PHARMACOLOGY (2004)
Contribution of redox-active iron and copper to oxidative damage in Alzheimer disease
RJ Castellani et al.
AGEING RESEARCH REVIEWS (2004)
Iron, brain ageing and neurodegenerative disorders
L Zecca et al.
NATURE REVIEWS NEUROSCIENCE (2004)
The genetic spectrum of human neuronal ceroid-lipofuscinoses
SE Mole
BRAIN PATHOLOGY (2004)
Current state of clinical and morphological features in human NCL
HH Goebel et al.
BRAIN PATHOLOGY (2004)
Lysosomal enzymes promote mitochondrial oxidant production, cytochrome c release and apoptosis
M Zhao et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2003)
Cathepsin D triggers bax activation, resulting in selective apoptosis-inducing factor (AIF) relocation in T lymphocytes entering the early commitment phase to apoptosis
N Bidère et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Multiple signaling events in amyloid β-induced, oxidative stress-dependent neuronal apoptosis
E Tamagno et al.
FREE RADICAL BIOLOGY AND MEDICINE (2003)
Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine
P Boya et al.
ONCOGENE (2003)
Intralysosomal iron: A major determinant of oxidant-induced cell death
ZQ Yu et al.
FREE RADICAL BIOLOGY AND MEDICINE (2003)
Lysosomal activation is a compensatory response against protein accumulation and associated synaptopathogenesis - An approach for slowing Alzheimer disease?
J Bendiske et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2003)
At the acidic edge: emerging functions for lysosomal membrane proteins
EL Eskelinen et al.
TRENDS IN CELL BIOLOGY (2003)
Lysosomes and brain aging in mammals
G Lynch et al.
NEUROCHEMICAL RESEARCH (2003)
Oxidative stress in brain aging - Implications for therapeutics of neurodegenerative diseases
RA Floyd et al.
NEUROBIOLOGY OF AGING (2002)
Lipofuscin: Mechanisms of age-related accumulation and influence on cell function
UT Brunk et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
Microinjection of cathepsin D induces caspase-dependent apoptosis in fibroblasts
K Roberg et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Delayed oxidant-induced cell death involves activation of phospholipase A2
M Zhao et al.
FEBS LETTERS (2001)
Bcl-2 phosphorylation is required for inhibition of oxidative stress-induced lysosomal leak and ensuing apoptosis
M Zhao et al.
FEBS LETTERS (2001)
Zinc resistance impairs sensitivity to oxidative stress in HeLa cells: Protection through metallothioneins expression
F Chimienti et al.
FREE RADICAL BIOLOGY AND MEDICINE (2001)
Sphingosine-induced apoptosis is dependent on lysosomal proteases
K Kågedal et al.
BIOCHEMICAL JOURNAL (2001)
Chloroquine-induced neuronal cell death is p53 and Bcl-2 family-dependent but caspase-independent
AU Zaidi et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2001)
Involvement of nitric oxide released from microglia-macrophages in pathological changes of cathepsin D-deficient mice
H Nakanishi et al.
JOURNAL OF NEUROSCIENCE (2001)
Caspases, apoptosis, and Alzheimer disease: Causation, correlation, and confusion
KA Roth
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2001)
Autophagic cell death and its execution by lysosomal cathepsins
Y Uchiyama
ARCHIVES OF HISTOLOGY AND CYTOLOGY (2001)
Methylmercury and H2O2 provoke lysosomal damage in human astrocytoma D384 cells followed by apoptosis
E Daré et al.
FREE RADICAL BIOLOGY AND MEDICINE (2001)
Apoptosis induced by exposure to a low steady-state concentration of H2O2 is a consequence of lysosomal rupture
F Antunes et al.
BIOCHEMICAL JOURNAL (2001)
The lysosomal protease cathepsin D mediates apoptosis induced by oxidative stress
K Kågedal et al.
FASEB JOURNAL (2001)
Lysosomal protease pathways to apoptosis -: Cleavage of Bid, not pro-caspases, is the most likely route
V Stoka et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Lysosomal membrane damage in soluble Aβ-mediated cell death in Alzheimer's disease
K Ditaranto et al.
NEUROBIOLOGY OF DISEASE (2001)
Cathepsin B contributes to TNF-α-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c
ME Guicciardi et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons
M Koike et al.
JOURNAL OF NEUROSCIENCE (2000)
Endocytic pathway abnormalities precede amyloid β deposition in sporadic Alzheimer's disease and Down syndrome -: Differential effects of APOE genotype and presenilin mutations
AM Cataldo et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
A mutation in the ovine cathepsin D gene causes a congenital lysosomal storage disease with profound neurodegeneration
J Tyynelä et al.
EMBO JOURNAL (2000)
Amyloid beta-induced neuronal death is bax-dependent but caspase-independent
LA Selznick et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2000)
Induction of cell death by the lysosomotropic detergent MSDH
W Li et al.
FEBS LETTERS (2000)
Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis
E Daugas et al.
FASEB JOURNAL (2000)
Up-regulation of the lysosomal system in experimental models of neuronal injury: Implications for Alzheimer's disease
E Adamec et al.
NEUROSCIENCE (2000)