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注意：仅列出部分参考文献，下载原文获取全部文献信息。Role of the multifunctional DNA repair and redox signaling protein Ape1/Ref-1 in cancer and endothelial cells: Small-molecule inhibition of the redox function of Ape1
Meihua Luo et al.
ANTIOXIDANTS & REDOX SIGNALING (2008)
Knockdown of the DNA repair and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell and tumor growth
Melissa L. Fishel et al.
DNA REPAIR (2008)
APE1/Ref-1 regulates PTEN expression mediated by Egr-1
Damiano Fantini et al.
FREE RADICAL RESEARCH (2008)
Redox factor-1 mediates NF-κB nuclear translocation for LPS-induced iNOS expression in murine macrophage cell line RAW 264.7
Ju Dong Song et al.
IMMUNOLOGY (2008)
Bcl2 inhibits abasic site repair by down-regulating APE1 endonuclease activity
Jinfeng Zhao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Unusual role of a cysteine residue in substrate binding and activity of human AP-endonuclease 1
Anil K. Mantha et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
TRAF2 and p38 are involved in B cells CD40-mediated APE/Ref-1 nuclear translocation: A novel pathway in B cell activation
Sonia Merluzzi et al.
MOLECULAR IMMUNOLOGY (2008)
A new APE1/Ref-1-dependent pathway leading to reduction of NF-κB and AP-1, and activation of their DNA-binding activity
Kozue Ando et al.
NUCLEIC ACIDS RESEARCH (2008)
Regulation of the human AP-endonuclease (APE1/Ref-1) expression by the tumor suppressor p53 in response to DNA damage
Amira Zaky et al.
NUCLEIC ACIDS RESEARCH (2008)
ATF4-Dependent oxidative induction of the DNA repair enzyme ape1 counteracts arsenite cytotoxicity and suppresses arsenite-mediated mutagenesis
Hua Fung et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Helicobacter pylori infection induces oxidative stress and programmed cell death in human gastric epithelial cells
Song-Ze Ding et al.
INFECTION AND IMMUNITY (2007)
The DNA base excision repair protein Ape1/Ref-1 as a therapeutic and chemopreventive target
Melissa L. Fishel et al.
MOLECULAR ASPECTS OF MEDICINE (2007)
Spatial coordination of cell-adhesion molecules and redox cycling of iron in the microvascular inflammatory response to pulmonary injury
Nikolai V. Gorbunov et al.
ANTIOXIDANTS & REDOX SIGNALING (2007)
Nitric oxide controls nuclear export of APE1/Ref-1 through S-nitrosation of Cysteines 93 and 310
Jing Qu et al.
NUCLEIC ACIDS RESEARCH (2007)
Ape1 regulates hematopoietic differentiation of embryonic stem cells through its redox functional domain
Gang-Ming Zou et al.
BLOOD (2007)
被撤回的出版物: Down-regulation of apurinic/apyrimidinic endonuclease 1/redox factor-1 expression by soy isoflavones enhances prostate cancer radiotherapy in vitro and in vivo (Retracted article. See vol. 78, pg. 6028, 2018)
Julian J. Raffoul et al.
CANCER RESEARCH (2007)
Interleukin-8 induction by Helicobacter pylori in gastric epithelial cells is dependent on apurinic/apyrimidinic endonuclease-1/redox factor-1
Ann M. O'Hara et al.
JOURNAL OF IMMUNOLOGY (2006)
Acetylation of human 8-oxoguanine-DNA glycosylase by p300 and its role in 8-oxoguanine repair in vivo
KK Bhakat et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
The transcription factor Egr1 is a direct regulator of multiple tumor suppressors including TGFβ1, PTEN, p53, and fibronectin
V Baron et al.
CANCER GENE THERAPY (2006)
Apurinic/apyrimidinic endonuclease1/redox factor-1 inhibits monocyte adhesion in endothelial cells
CS Kim et al.
CARDIOVASCULAR RESEARCH (2006)
Identification and characterization of mitochondrial abasic (AP)-endonuclease in mammalian cells
Ranajoy Chattopadhyay et al.
NUCLEIC ACIDS RESEARCH (2006)
Acetylation and deacetylation of non-histone proteins
MA Glozak et al.
GENE (2005)
Increased nuclear localization of transcription factor Y-box binding protein 1 accompanied by up-regulation of P-glycoprotein in breast cancer pretreated with paclitaxel
T Fujita et al.
CLINICAL CANCER RESEARCH (2005)
Synthesis of chemical probes to map sulfenic acid modifications on proteins
LB Poole et al.
BIOCONJUGATE CHEMISTRY (2005)
Apurinic/apyrimidinic endonuclease activity is associated with response to radiation and chemotherapy in medulloblastoma and primitive neuroectodermal tumors
MS Bobola et al.
CLINICAL CANCER RESEARCH (2005)
S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding
MR Hara et al.
NATURE CELL BIOLOGY (2005)
Redox redux: Revisiting PTPs and the control of cell signaling
NK Tonks
CELL (2005)
Induction of DNA repair proteins, Ref-1 and XRCC1, in adult rat brain following kainic acid-induced seizures
N Quach et al.
BRAIN RESEARCH (2005)
Protein-protein interactions and posttranslational modifications in mammalian base excision repair
JS Fan et al.
FREE RADICAL BIOLOGY AND MEDICINE (2005)
HIF-1α, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complexthat regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas
MJ Gray et al.
ONCOGENE (2005)
Two essential but distinct functions of the mammalian abasic endonuclease
T Izumi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
The multifunctional DNA repair/redox enzyme Ape1/Ref-1 promotes survival of neurons after oxidative stress
MR Vasko et al.
DNA REPAIR (2005)
The intracellular localization of APE1/Ref-1: More than a passive phenomenon?
G Tell et al.
ANTIOXIDANTS & REDOX SIGNALING (2005)
Cross-regulation between Egr-1 and APE/Ref-1 during early response to oxidative stress in the human osteoblastic HOBIT cell line: Evidence for an autoregulatory loop
A Pines et al.
FREE RADICAL RESEARCH (2005)
Redox factor 1 (Ref-1) enhances specific DNA binding of p53 by promoting p53 tetramerization
S Hanson et al.
ONCOGENE (2005)
A vital role for Ape1/Ref1 protein in repairing spontaneous DNA damage in human cells
H Fung et al.
MOLECULAR CELL (2005)
Redox regulation of protein-tyro sine phosphatases
J den Hertog et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2005)
Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP
A Pines et al.
NUCLEIC ACIDS RESEARCH (2005)
Analysis of nuclear transport signals in the human apurinic/apyrimidinic endonuclease (APE1/Ref1)
EB Jackson et al.
NUCLEIC ACIDS RESEARCH (2005)
Ref-1/Ape is critical for formation of the hypoxia-inducible transcriptional complex on the hypoxic response element of the rat pulmonary artery endothelial cell VEGF gene
KA Ziel et al.
FASEB JOURNAL (2004)
CD40 stimulation induces Pax5/BSAP and EBF activation through a APE/ref-1-dependent redox mechanism
S Merluzzi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Effects of gemcitabine on APE/ref-1 endonuclease activity in pancreatic cancer cells, and the therapeutic potential of antisense oligonucleotides
JP Lau et al.
BRITISH JOURNAL OF CANCER (2004)
Helicobacter pylori and H2O2 increase AP endonuclease-1/redox factor-1 expression in human gastric epithelial cells
SZ Ding et al.
GASTROENTEROLOGY (2004)
AP endonuclease-independent DNA base excision repair in human cells
L Wiederhold et al.
MOLECULAR CELL (2004)
Direct effects of recombinant human endostatin on tumor cell IL-8 production are associated with increased endothelial cell apoptosis in an orthotopic model of human pancreatic cancer
CP Raut et al.
CANCER BIOLOGY & THERAPY (2004)
Acetylation of the human DNA glycosylase NEIL2 and inhibition of its activity
KK Bhakat et al.
NUCLEIC ACIDS RESEARCH (2004)
Apurinic/apyrmidinic endonuclease 1 regulates endothelial NO production and vascular tone
BH Jeon et al.
CIRCULATION RESEARCH (2004)
Role of acetylated human AP-endonuclease (APE1/Ref-1) in regulation of the parathyroid hormone gene
KK Bhakat et al.
EMBO JOURNAL (2003)
Mammalian DNA base excision repair proteins: their interactions and role in repair of oxidative DNA damage
T Izumi et al.
TOXICOLOGY (2003)
APE/Ref-1 and the mammalian response to genotoxic stress
G Fritz et al.
TOXICOLOGY (2003)
Is DNA repair compromised in Alzheimer's disease?
V Davydov et al.
NEUROBIOLOGY OF AGING (2003)
Stat3 protects against Fas-induced liver injury by redox-dependent and -independent mechanisms
S Haga et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
The pleiotropic functions of the Y-box-binding protein, YB-1
K Kohno et al.
BIOESSAYS (2003)
Cysteine 64 of Ref-1 is not essential for redox regulation of AP-1 DNA binding
JM Ordway et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Implication of Ref-1 in the repression of renin gene transcription by intracellular calcium
S Fuchs et al.
JOURNAL OF HYPERTENSION (2003)
Regulation and destabilization of HIF-1α by ARD1-mediated acetylation
JW Jeong et al.
CELL (2002)
Spatial redox regulation of a critical cysteine residue of NF-κB in vivo
T Nishi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Selenomethionine regulation of p53 by a ref1-dependent redox mechanism
YR Seo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Oxidoreductive modification of two cysteine residues in paired domain by Ref-1 regulates DNA-binding activity of Pax-8
X Cao et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Control of Smad7 stability by competition between acetylation and ubiquitination
E Grönroos et al.
MOLECULAR CELL (2002)
Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesions
TK Hazra et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Choreography of oxidative damage repair in mammalian genomes
S Mitra et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
Redox factor-1: an extra-nuclear role in the regulation of endothelial oxidative stress and apoptosis
P Angkeow et al.
CELL DEATH AND DIFFERENTIATION (2002)
Human AP-endonuclease 1 and hnRNP-L interact with a nCaRE-like repressor element in the AP-endonuclease 1 promoter
DT Kuninger et al.
NUCLEIC ACIDS RESEARCH (2002)
The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling
T Virolle et al.
NATURE CELL BIOLOGY (2001)
Key role of a downstream specificity protein 1 site in cell cycle-regulated transcription of the AP endonuclease gene APE1/APEX in NIH3T3 cells
H Fung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Interaction of human AP endonuclease 1 with flap endonuclease 1 and proliferating cell nuclear antigen involved in long-patch base excision repair
II Dianova et al.
BIOCHEMISTRY (2001)
Redox regulation of the DNA repair function of the human AP endonuclease Ape1/ref-1
MR Kelley et al.
ANTIOXIDANTS & REDOX SIGNALING (2001)
Activation of APE/Ref-1 redox activity is mediated by reactive oxygen species and PKC phosphorylation
MM Hsieh et al.
NUCLEIC ACIDS RESEARCH (2001)
Overexpression of Ref-1 inhibits hypoxia and tumor necrosis factor-induced endothelial cell apoptosis through nuclear factor-κB-independent and -dependent pathways
JL Hall et al.
CIRCULATION RESEARCH (2001)
Oxidative cellular damage and the reduction of APE/Ref-1 expression after experimental traumatic brain injury
A Lewén et al.
NEUROBIOLOGY OF DISEASE (2001)
Nuclear expression of human apurinic/apyrimidinic endonuclease (HAP1/REF-1) in head-and-neck cancer is associated with resistance to chemoradiotherapy and poor outcome
MI Koukourakis et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2001)
Mitochondrial localization of APE/Ref-1 in thyroid cells
G Tell et al.
MUTATION RESEARCH-DNA REPAIR (2001)
XRCC1 stimulates human polynucleotide kinase activity at damaged DNA termini and accelerates DNA single-strand break repair
CJ Whitehouse et al.
CELL (2001)
Induction of Ref-1 ensures AP-1 activation in intracellular oxidative environment of IL-2-stimulated BA/F3β cells
MD Yan et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
Going APE over ref-1
AR Evans et al.
MUTATION RESEARCH-DNA REPAIR (2000)
Requirement for human AP endonuclease 1 for repair of 3′-blocking damage at DNA single-strand breaks induced by reactive oxygen species
T Izumi et al.
CARCINOGENESIS (2000)
TSH controls Ref-1 nuclear translocation in thyroid cells
G Tell et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2000)
DNA-bound structures and mutants reveal abasic DNA binding by APE1 DNA repair and coordination
CD Mol et al.
NATURE (2000)
Redox-regulated recruitment of the transcriptional coactivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1 alpha
P Carrero et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
An 'environment to nucleus' signaling system operates in B lymphocytes: redox status modulates BSAP/Pax-5 activation through Ref-1 nuclear translocation
G Tell et al.
NUCLEIC ACIDS RESEARCH (2000)
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