4.7 Article

The First NDM Metallo-β-Lactamase-Producing Enterobacteriaceae Isolate in Poland: Evolution of IncFII-Type Plasmids Carrying the blaNDM-1 Gene

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ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 58, 期 2, 页码 1203-1207

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AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01197-13

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  1. Narodowy Program Ochrony AntybiotykOw (NPOA) from the Polish Ministry of Health
  2. SPUB MIKROBANK from the Polish Ministry of Science and Higher Educatio

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Poland's first Enterobacteriaceae isolate producing the New Delhi metallo-beta-lactamase (NDM) was identified in August 2011. Escherichia coli sequence type ST410 NDM-1 was cultured from a critically ill patient who had been transferred directly from the Congo. The bla(NDM-1) gene was carried by conjugative IncFII-type plasmid pMC-NDM (87,619 bp), which showed structural similarity to plasmid pGUE-NDM, which was identified earlier in France in an E. coli ST131 isolate of Indian origin.

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