4.7 Article

Comparison between the EUCAST Procedure and the Etest for Determination of the Susceptibility of Candida Species Isolates to Micafungin

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ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 57, 期 11, 页码 5767-5770

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AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01032-13

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资金

  1. Fondo de Investigacion Sanitaria (FIS) [PI11/00167]
  2. Astellas Pharma
  3. FIS [CD09/00230, MS09/00055, FI12/00265, CD11/00110]

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We compared the ability of the EUCAST EDef 7.2 and the Etest to detect the susceptibility to micafungin of 160 Candida and non-Candida clinical isolates. Agreement was higher when Etest MICs were obtained after 24 h of incubation; essential agreement was 90%, and categorical agreement was >90%. False susceptibility was seen only for Candida krusei (10%), and false resistance was observed in 6% of the isolates, ranging from 2.6% (C. glabrata) to 13% (C. albicans).

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