期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 58, 期 3, 页码 1806-1808出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.02101-13
关键词
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资金
- Ministerio de Ciencia e Innovacion, Instituto de Salud Carlos III
- European Development Regional Fund A way to achieve Europe ERDF, Spanish Network for the Research in Infectious Diseases [REIPI RD06/0008]
- Consejeria de Innovacion, Ciencia y Empresa [CTS 6317/10]
Acinetobacter baumannii has emerged as a nosocomial pathogen with an increased prevalence of multidrug-resistant strains. The role of the outer membrane protein A (OmpA) in antimicrobial resistance remains poorly understood. In this report, disruption of the ompA gene led to decreased MICs of chloramphenicol, aztreonam, and nalidixic acid. We have characterized, for the first time, the contribution of OmpA in the antimicrobial resistance phenotype of A. baumannii.
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