期刊
CURRENT ORGANIC CHEMISTRY
卷 9, 期 15, 页码 1535-1549出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/138527205774370478
关键词
-
Molybdenum and ruthenium alkylidene-catalyzed ring-closing metathesis (RCM) reactions have emerged as key constructs for the facile assembly of the polycyclic frameworks of a variety of natural products. Advances in catalyst development, particularly of highly reactive ruthenium species, have enabled facile ene-ene and ene-yne bond metatheses to create both carbocyclic and heterocyclic systems, sometimes possessing remarkable functional and structural complexity in a single operation. The operational simplicity, ease of handling, and generally high turnover numbers of the ruthenium-catalysts have brought RCM reactions to the forefront of practical carbon-carbon bond forming transformations. Some recent applications of RCM to the synthesis of alkaloid natural products are reviewed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据