4.4 Article

Microwave-assisted addition of pyrroles to electron-deficient olefins:: A rapid entry to C-alkyl pyrroles

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SYNLETT
卷 -, 期 16, 页码 2425-2428

出版社

GEORG THIEME VERLAG KG
DOI: 10.1055/s-2005-872688

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microwave irradiation; bismuth trichloride; pyrroles; electron-deficient olefins; Michael reaction

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A general procedure for the Michael addition of pyrroles with electron-deficient olefins Using silica gel supported reagent under microwave irradiation, has been developed. This new method is fast, efficient, environmentally benign and solvent-free. A catalytic amount of BiCl3 is employed For moderately bulk electron-deficient olefins.

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