期刊
SCIENCE
卷 310, 期 5745, 页码 111-113出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1117623
关键词
-
Delta oscillations, characteristic of the electroencephalogram (EEG) of slow wave steep, estimate sleep depth and need and are thought to be closely linked to the recovery function of sleep. The cellular mechanisms underlying the generation of delta waves at the cortical and thalamic levels are well documented, but the molecular regulatory mechanisms remain elusive. Here we demonstrate in the mouse that the gene encoding the retinoic acid receptor beta determines the contribution of delta oscillations to the steep EEG. Thus, retinoic acid signaling, which is involved in the patterning of the brain and dopaminergic pathways, regulates cortical synchrony in the adult.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据