4.7 Article

A Staphylococcus xylosus Isolate with a New mecC Allotype

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ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 57, 期 3, 页码 1524-1528

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AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01882-12

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资金

  1. Medical Research Council Partnership grant [G1001787/1]
  2. School of Clinical Medicine, University of Cambridge
  3. Moredun Research Institute
  4. Wellcome Trust Sanger Institute
  5. Medical Research Council [G1001787] Funding Source: researchfish
  6. MRC [G1001787] Funding Source: UKRI

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Recently, a novel variant of mecA known as mecC (mecA(LGA251)) was identified in Staphylococcus aureus isolates from both humans and animals. In this study, we identified a Staphylococcus xylosus isolate that harbors a new allotype of the mecC gene, mecC1. Whole-genome sequencing revealed that mecC1 forms part of a class E mec complex (mecI-mecR1-mecC1-blaZ) located at the orfX locus as part of a likely staphylococcal cassette chromosome mec element (SCCmec) remnant, which also contains a number of other genes present on the type XI SCCmec.

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