期刊
NEUROLOGY
卷 65, 期 7, 页码 1094-1097出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1212/01.wnl.0000179003.95838.71
关键词
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资金
- NCRR NIH HHS [R21 RR019771-01, M01 RR00865, P41 RR013642-08, P41 RR013642, P41 RR13642, M01 RR000865-26, R21 RR019771, M01 RR000865] Funding Source: Medline
- NIA NIH HHS [P50 AG016570] Funding Source: Medline
- NIBIB NIH HHS [R21 EB01651] Funding Source: Medline
The authors used surface-based anatomic mapping to detect features of hippocampal anatomy that correlated with surgical outcomes in patients undergoing surgery for mesial temporal lobe epilepsy with hippocampal sclerosis. Compared with a seizure-free group, hippocampal profiles for the non-seizure-free group had greater diffuse ipsilateral atrophy and more region-specific contralateral atrophy in the anterior, lateral hippocampus. These atrophic regions may indicate areas of increased epileptogenicity, contributing to poorer surgical outcomes.
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