期刊
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 15, 期 20, 页码 4506-4509出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2005.07.010
关键词
porphyrinogens; oxidative enzymes; heme biosynthesis; coproporphyrinogen oxidase; porphyria
资金
- NIGMS NIH HHS [1R15GM/OD 52687-01A1] Funding Source: Medline
A new mechanism is proposed to explain how coproporphyrinogen oxidase performs two oxidative decarboxylations on a porphyrinogen substrate without the aid of cofactors or metal ions in the presence of molecular oxygen. (c) 2005 Elsevier Ltd. All rights reserved.
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