期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 127, 期 41, 页码 14473-14478出版社
AMER CHEMICAL SOC
DOI: 10.1021/ja054169u
关键词
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In this work, we show the strong resistance of zwitterionic phosphorylcholine (PC) self-assembled monolayers (SAMS) to protein adsorption and examine key factors leading to their nonfouling behavior using both experimental and molecular simulation techniques. Zwitterions with a balanced charge and minimized dipole are excellent candidates as nonfouling materials due to their strong hydration capacity via electrostatic interactions.
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