期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 55, 期 6, 页码 3022-3024出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01732-10
关键词
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资金
- Australian National Health and Medical Research Council
- Australian Postgraduate Award scholarship
Infections caused by Acinetobacter baumannii are of increasing concern, largely due to the multidrug resistance of many strains. Here we show that insertion sequence ISAba11 movement can result in inactivation of the A. baumannii lipid A biosynthesis genes lpxA and lpxC, resulting in the complete loss of lipopolysaccharide production and high-level colistin resistance.
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