4.7 Article

Emergence of Carbapenem-Resistant Non-baumannii Species of Acinetobacter Harboring a blaOXA-51-Like Gene That Is Intrinsic to A. baumannii

期刊

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 56, 期 2, 页码 1124-1127

出版社

AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00622-11

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资金

  1. Taipei Veterans General Hospital [V100C-025, V10E4-005]
  2. National Science Council [NSC98-2314-B-010-010-MY3]
  3. Yen Tjing Ling Medical Foundation [CI-99-18]

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The bla(OXA-51)-like gene, originally intrinsic to Acinetobacter baumannii, had been detected in two clones of Acinetobacter nosocomialis and one clone of Acinetobacter genomic species Close to 13TU. These bla(OXA-51)-like genes, all preceded by ISAbal, were located on plasmids that might have originated with A. baumannii. The plasmid-borne ISAbal-blac(OXA-51)-like confers a high level of carbapenem resistance and affects the accuracy of using bla(OXA-51)-like detection as a tool for differentiating A. baumannii from other Acinetobacter species.

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