期刊
FEBS LETTERS
卷 579, 期 25, 页码 5501-5506出版社
WILEY
DOI: 10.1016/j.febslet.2005.08.081
关键词
beta-hexosaminidase; lysosomal enzyme; plasma membrane
资金
- NINDS NIH HHS [NS 09626] Funding Source: Medline
Mature beta-hexosaminidase A has been found associated to the external leaflet of plasma membrane of cultured fibroblasts. The plasma membrane association of P-hexosaminidase A has been directly determined by cell surface biotinylation followed by affinity chromatography purification of the biotinylated proteins, and by immunocytochemistry. The immunological and biochemical characterization of biotinylated beta-hexosaminidase A revealed that the plasma membrane associated enzyme is fully processed, suggesting its lysosomal origin. (c) 2005 Published by Elsevier B.V. on behalf of the Federation of European Biochemical Societies.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据