期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 55, 期 2, 页码 934-936出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01247-10
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资金
- INSERM, Paris, France [U914]
- Ministere de l'Education Nationale et de la Recherche [UPRES-EA3539]
- Universite Paris XI, Paris, France
- European Community [HEALTH-2009-241742]
Seven carbapenem-resistant NDM-1-positive Klebsiella pneumoniae isolates were recovered from patients hospitalized between 2007 and 2009 in different wards at a referral and tertiary care center in Nairobi. Most of the isolates were obtained from urine. All isolates carried the bla(NDM-1) carbapenemase gene previously reported from India, Pakistan, and the United Kingdom. These isolates were clonally related and expressed many other resistance determinants, including beta-lactamases CTX-M-15, OXA-1, OXA-9, CMY-6, and aminoglycoside resistance methylase RmtC. This work corresponds to the first report of NDM-1 producers in Africa.
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