期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 54, 期 5, 页码 2262-2264出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.01423-09
关键词
-
Murine models of Mycobacterium tuberculosis infection are essential tools in drug discovery. Here we describe a fast standardized 9-day acute assay intended to measure the efficacy of drugs against M. tuberculosis growing in the lungs of immunocompetent mice. This assay is highly reproducible, allows good throughput, and was validated for drug lead optimization using isoniazid, rifampin, ethambutol, pyrazinamide, linezolid, and moxifloxacin.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据