4.7 Article

Detection of KPC in Acinetobacter spp. in Puerto Rico

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ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 54, 期 3, 页码 1354-1357

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AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00899-09

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  1. Janssen Ortho-McNeil, Inc.
  2. Merck Sharp and Dohme, Inc.
  3. Pfizer, Inc.
  4. NCRR/NIH-RCMI [G12RR03051]

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During an island-wide PCR-based surveillance study of beta-lactam resistance in multidrug-resistant (MDR) Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter calcoaceticus-baumannii complex isolates obtained from 17 different hospitals, 10 KPC-positive Acinetobacter isolates were identified. DNA sequencing of the bla(KPC) gene identified KPC-2, -3, and -4 and a novel variant, KPC-10. This is the first report of a KPC-type beta-lactamase identified in Acinetobacter species.

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