期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 53, 期 9, 页码 4013-4014出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00584-09
关键词
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资金
- Spanish Ministry of Health [FIS 08/00195, 2005SGR-00956]
- Ministerio de Sanidad y Consumo, Instituto de Salud Carlos III-FEDER
- Spanish Network for the Research in Infectious Diseases [REIPI RD06/0008]
- European Community [HEALTH-F3-2008-223101]
Acinetobacter baumannii has been increasingly associated with hospital-acquired infections, and the presence of multidrug resistance strains is of great concern to clinicians. A. baumannii is thought to possess a great deal of intrinsic resistance to several antimicrobial agents, including chloramphenicol, although the mechanisms involved in such resistance are not well understood. In this work, we have identified a major facilitator superfamily efflux pump present in most A. baumannii strains, displaying strong substrate specificity toward chloramphenicol.
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