期刊
SEMINARS IN DIAGNOSTIC PATHOLOGY
卷 22, 期 4, 页码 273-283出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1053/j.semdp.2006.04.001
关键词
gastritis; gastropathy; chemical gastropathy; reactive gastropathy; foveolar hyperplasia; erosions; drug-induced damage; nonsteroidal antiinflammatory agents; bile reflux
Reactive or chemical gastropathy is the constellation of endoscopic and histological changes caused by chemical injury to the gastric mucosa. Its diagnosis rests on the histopathological demonstration of nonspecific elementary lesions that may occur simultaneously or separately in different degrees and various proportions. These lesions include foveolar hyperplasia, interfoveolar smooth muscle fibers, erosions, edema, and hyperemia, in the absence of significant inflammation. Their respective occurrence in a set of gastric biopsies can be placed on a spectrum of diagnostic certainty that is never absolute because each of such changes can and does occur in other conditions. Although a correlation between histological evidence of chemical gastropathy and clinical manifestations, particularly risk of bleeding, is yet to be documented, reporting the suspicion of drug-induced gastric damage may help clinicians to identify patients that might benefit from change, reduction, or discontinuation of certain medications. This is a US government work. There are no restrictions on its use.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据