期刊
MYCOSES
卷 48, 期 6, 页码 456-461出版社
WILEY
DOI: 10.1111/j.1439-0507.2005.01150.x
关键词
chromoblastomycosis; Phialophora verrucosa; black yeast; rDNA Internal Transcribed Spacer; human infection
We report on a severe, verrucous facial mycosis and sinusitis in a 12-year-old Libyan girl. Her disease started with verrucous, hyperkeratotic plaques and subcutaneous violet nodules of unknown origin on her face and upper extremities. Despite topical antimycotic therapy she needed in-hospital treatment because of severely progressive tumorous cutaneous and nasal lesions. Microscopic examination of scale samples taken from the upper extremities and the face revealed brown, thick-walled fungal elements. Under the assumption of a chromoblastomycosis, an oral treatment with itraconazole and fluorocytosin was initiated, with significant improvement of the lesions. The aetiological agent was identified as Phialophora verrucosa.
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