期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 52, 期 9, 页码 3418-3423出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.00336-08
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In phase 3 clinical trials for ceftobiprole treatment of complicated skin and skin structure infections, 1,219 gram-positive and 276 gram-negative aerobic baseline pathogens were identified. Ceftobiprole inhibited all staphylococcal isolates, including methicillin-resistant strains, at MICs of <= 4 mu g/ml. Against Enterobacteriaceae and Pseudomonas aeruginosa isolates, the potency of ceftobiprole was similar to that of cefepime.
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