期刊
JOURNAL OF COMPARATIVE PATHOLOGY
卷 133, 期 4, 页码 281-285出版社
ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD
DOI: 10.1016/j.jcpa.2005.04.008
关键词
bacterial infection; Helicobacter heilmannii; invasiveness; Leopardus pardalis; ocelot; parietal cell
Highly invasive Helicobacter-like organisms were found in a 19-year-old female ocelot (Leopardus pardalis) with multiple ulcers in the fundic region of the stomach. The bacteria, resembling Helicobacter heilmannii, were located largely within canaliculi or in the cytosol of parietal cells. Except in the ulcerative lesions, parietal cells were hyperplastic, while chief cells and neck mucous cells were reduced in number. The term gastroinvasive Helicobacter-like organism was applied. It seems probable that this organism differs from other Helicobacter organisms in pathogenicity, and possible that its behaviour in vitro would help it to evade antibacterial treatment. (c) 2005 Elsevier Ltd. All rights reserved.
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