期刊
FEMS MICROBIOLOGY LETTERS
卷 252, 期 1, 页码 67-72出版社
OXFORD UNIV PRESS
DOI: 10.1016/j.femsle.2005.08.025
关键词
Listeria monocytogenes; nisin resistance; antibiotic cross-resistance; synthetic antimicrobial peptides; surface properties
类别
The antibiotic susceptibility of wild Listeria monocytogenes strains and their corresponding nisin resistant variants was assessed. The resistant strains were more sensitive to most of the tested antibiotics than their wild-type counterparts. A slight increase in MIC was observed for a few antibiotics including the membrane disturbing polymixin B. Cross-resistance was detected with two synthetic antimicrobial peptides. A lower C15/C17 ratio in the membrane fatty acid composition of the nisin resistant strains was found, and one strain pair showed a significant difference in surface hydrophobicity. As judged by these results, no clear correlation could be established between resistance to nisin and to worldwide-used antibiotics. (c) 2005 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved.
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