期刊
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
卷 12, 期 6, 页码 611-618出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/187152012800617713
关键词
Anticancer activity; Anti-inflammatory; 1,4-benzodiazepines; Myeloperoxidase
资金
- DGAPA-UNAM [IN202010-3]
A series of 5-aryl-1,4-benzodiazepines with chloro- or fluoro-substituents in the second ring have been synthesized and their anti-inflammatory, myeloperoxidase and anticancer properties studied. The synthesized compounds showed potential anti-inflammatory and anticancer activities, which were enhanced in the presence of a chloro- substituent in the second ring of the 5-aryl-1,4-benzodiazepine.
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