4.4 Article

Natural Products: Promising Resources for Cancer Drug Discovery

期刊

出版社

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/187152012798764697

关键词

Apoptosis; Chemoprevention; Immunotherapy; Lead molecule; Medicinal plants

资金

  1. Council of Scientific and Industrial Research (CSIR) under New Millennium Indian Technology leadership Initiative (NMITLI) [IAP-0001, HCP004, TLP-004]
  2. CSIR-I.I.C.B.
  3. Department of Biotechnology, Govt. of India [GAP 235]
  4. Department of Science and Technology, Govt. of India

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Natural products are important sources of anti-cancer lead molecules. Many successful anti-cancer drugs are natural products or their analogues. Many more are under clinical trials. The present review focuses on chemopreventive and anti-cancer activities of polar and non-polar extracts, semi purified fractions and pure molecules from terrestrial plants of India reported between 2005 and 2010 emphasizing possible mechanisms of action of pure molecules.

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