G-taff teLomere HPA: simple measurement of human single-stranded telomeric overhangs

Accurate measurement of telomeric 3'-overhang (G-tail) lengths is essential for investigation of the biological effects of telomere dysfunction. G-tail telomere hybridization protection assay (Gt-tetomere HPA) has the advantages of being simple to perform, accurate and highly sensitive for G tails as short as 20 nucleotides. Furthermore, Gt-tetomere HPA is specific and quantitative for human G tails, and can be used to assay cell lysates as well as genomic DNA.