期刊
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
卷 15, 期 6, 页码 1213-1217出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1111/j.1525-1438.2005.00190.x
关键词
benign metastasizing leiomyoma; lung neoplasm; megestrol; progesterone
Benign metastasizing leiomyoma (BML) is an unusual condition typically treated by surgical resection and hormonal therapy. A 37-year-old woman presented with dyspnea 6 years after uterine myomectomy. Computed tomographic scans showed pelvic and right-sided lung masses. Total abdominal hysterectomy and right salpingo-oophorectomy revealed only leiomyomas and benign ovarian cysts. Thoracotomy revealed multiple nodules consistent with leiomyomas. Estrogen and progesterone receptors on lung and uterine tissue were positive. A 21- x 18-mm residual area of neoplasm in the lung completely resolved 3 months after treatment with megestrol. The patient remains free of disease 3 years after lung resection. We present a rare case of BML in which the lung neoplasm responded to megestrol alone in the setting of intact ovarian function.
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