Transfusion-related acute lung injury

Purpose of review Transfusion-related acute lung injury is an uncommon complication of blood transfusion typically manifestedby shortness of breath, fever, and hypotension. Transfusion-related acuts lung injury is an important cause of transfusion-related morbidity and mortality. Recent findings much about the pathogenesis, treatment, and prevention of transfusion-related acute lung injury is poorly understood or is controversial. There is increasing recognition that transfusion-related acute lung injury is an important clinical syndrome, causing most transfusion-related deaths. Summary In this report, what is known about transfusion-related acute lung injury is summarized with particular emphasis on recent studies. Sme of the areas in which knowledge and/or consensus are currently lacking are identified.