期刊
ANALYTICA CHIMICA ACTA
卷 552, 期 1-2, 页码 127-134出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.aca.2005.07.040
关键词
vardenafil hydrochloride; voltammetry; drug analysis; oxidation mechanism
The voltammetric behavior of vardenafil was studied on glassy carbon electrode using cyclic, differential pulse (DPV) and Osteryoung square-wave (OSW) voltammetric techniques. Vardenafil exhibited irreversible anodic waves over the pH range 1.00-12.00 in different supporting electrolytes. The current-concentration plot was rectilinear over the range from 4 x 10(-7) to 2 x 10(-5) M with correlation coefficient of 0.999. The wave was characterized as being irreversible and diffusion-controlled. The developed procedure was successfully applied to the determination of vardenafil in tablets and in spiked human serum. Furthermore, results obtained by the proposed method have been compared with high-performance liquid chromatographic method. (c) 2005 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据