期刊
ANNUAL REVIEW OF PUBLIC HEALTH, VOL 31
卷 31, 期 -, 页码 53-68出版社
ANNUAL REVIEWS
DOI: 10.1146/annurev.publhealth.031809.130844
关键词
gene; nutrient; upregulation of genes; downregulation of genes; omega-6 and omega-3 fatty acids; novel foods; chronic diseases and public health
All diseases have a genetic predisposition. Genome-wide association studies (GWASs) by large international consortia are discovering genetic variants that contribute to complex diseases. However, nutrient information is missing, which is essential for the development of dietary advice for prevention and management of disease. Nutrigenetics/nutrigenomics studies provide data on mechanisms of nutrient and gene interactions in health and disease needed for personalized nutrition. A process will be needed to define when gene-nutrient-disease associations are ready to be evaluated as potential tools to improve public health.
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