期刊
OPTICS LETTERS
卷 30, 期 22, 页码 3048-3050出版社
OPTICAL SOC AMER
DOI: 10.1364/OL.30.003048
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资金
- Directorate For Engineering
- Div Of Chem, Bioeng, Env, & Transp Sys [0940321] Funding Source: National Science Foundation
We describe gold nanocages as a new class of potential contrast agent for spectroscopic optical coherence tomography (OCT). Monodispersed gold nanocages of an similar to 35 nm edge length exhibit strong optical resonance, with the peak wavelength tunable in the near-infrared range. We characterized the optical properties of the nanocage by using OCT experiments along with numerical calculations, revealing an absorption cross section approximately 5 orders of magnitude larger than conventional dyes. Experiments with tissue phantoms demonstrated that the nanocages provide enhanced contrast for spectroscopic as well as conventional intensity-based OCT imaging. (c) 2005 Optical Society of America.
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