相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Racial Differences in the Incidence of Mesenchymal Tumors Associated with EWSR1 Translocation
Jennifer Worch et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2011)
Identification of an Inhibitor of the EWS-FLI1 Oncogenic Transcription Factor by High-Throughput Screening
Patrick J. Grohar et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2011)
An Integrated Chemical Biology Approach Identifies Specific Vulnerability of Ewing's Sarcoma to Combined Inhibition of Aurora Kinases A and B
Georg E. Winter et al.
MOLECULAR CANCER THERAPEUTICS (2011)
A novel oncogenic mechanism in Ewing sarcoma involving IGF pathway targeting by EWS/Fli1-regulated microRNAs
E. L. McKinsey et al.
ONCOGENE (2011)
Mutational Inactivation of STAG2 Causes Aneuploidy in Human Cancer
David A. Solomon et al.
SCIENCE (2011)
Promiscuous partnerships in Ewing's sarcoma
Savita Sankar et al.
CANCER GENETICS (2011)
Function of EWS-POU5F1 in Sarcomagenesis and Tumor Cell Maintenance
Takashi Fujino et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Biological Rationale and Current Clinical Experience With Anti-Insulin-Like Growth Factor 1 Receptor Monoclonal Antibodies in Treating Sarcoma Twenty Years From the Bench to the Bedside
David Olmos et al.
CANCER JOURNAL (2010)
The EWS/FLI1 oncogenic protein inhibits expression of the Wnt inhibitor DICKKOPF-1 gene and antagonizes β-catenin/TCF-mediated transcription
Diego Navarro et al.
CARCINOGENESIS (2010)
A Phase I Study of Weekly R1507, A Human Monoclonal Antibody Insulin-like Growth Factor-I Receptor Antagonist, in Patients with Advanced Solid Tumors
Razelle Kurzrock et al.
CLINICAL CANCER RESEARCH (2010)
EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cells
Nicolo Riggi et al.
GENES & DEVELOPMENT (2010)
EWSR1-POU5F1 Fusion in Soft Tissue Myoepithelial Tumors. A Molecular Analysis of Sixty-Six Cases, Including Soft Tissue, Bone, and Visceral Lesions, Showing Common Involvement of the EWSR1 gene
Cristina R. Antonescu et al.
GENES CHROMOSOMES & CANCER (2010)
The Ewing's Sarcoma Fusion Protein, EWS-FLI, Binds Runx2 and Blocks Osteoblast Differentiation
Xiaodong Li et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2010)
Impact of EWS-ETS Fusion Type on Disease Progression in Ewing's Sarcoma/Peripheral Primitive Neuroectodermal Tumor: Prospective Results From the Cooperative Euro-EWING 99 Trial
Marie-Cecile Le Deley et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
Current Treatment Protocols Have Eliminated the Prognostic Advantage of Type 1 Fusions in Ewing Sarcoma: A Report From the Children's Oncology Group
John A. van Doorninck et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
Small Is Beautiful: Insulin-Like Growth Factors and Their Role in Growth, Development, and Cancer
Robert G. Maki
JOURNAL OF CLINICAL ONCOLOGY (2010)
IGF-1R targeted treatment of sarcoma
Jeffrey A. Toretsky et al.
LANCET ONCOLOGY (2010)
Safety, pharmacokinetics, and preliminary activity of the anti-IGF-1R antibody figitumumab(CP-751,871) in patients with sarcoma and Ewing's sarcoma: a phase 1 expansion cohort study
David Olmos et al.
LANCET ONCOLOGY (2010)
Nuclear reprogramming to a pluripotent state by three approaches
Shinya Yamanaka et al.
NATURE (2010)
De novo motif identification improves the accuracy of predicting transcription factor binding sites in ChIP-Seq data analysis
Valentina Boeva et al.
NUCLEIC ACIDS RESEARCH (2010)
Downstream EWS/FLI1-upstream Ewing's sarcoma
Heinrich Kovar
GENOME MEDICINE (2010)
Stable interference of EWS-FLI1 in an Ewing sarcoma cell line impairs IGF-1/IGF-1R signalling and reveals TOPK as a new target
D. Herrero-Martin et al.
BRITISH JOURNAL OF CANCER (2009)
Review of Mesenchymal Stem Cells and Tumors: Executioner or Coconspirator?
Bing Feng et al.
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2009)
Ewing sarcoma-peripheral neuroectodermal tumor of the kidney with a FUS-ERG fusion transcript
Thomas Berg et al.
CANCER GENETICS AND CYTOGENETICS (2009)
EWS/FLI and Its Downstream Target NR0B1 Interact Directly to Modulate Transcription and Oncogenesis in Ewing's Sarcoma
Michelle Kinsey et al.
CANCER RESEARCH (2009)
Advances in Ewing's Sarcoma Research: Where Are We Now and What Lies Ahead?
Jose Luis Ordonez et al.
CANCER RESEARCH (2009)
The NFATc2 Gene Is Involved in a Novel Cloned Translocation in a Ewing Sarcoma Variant That Couples Its Function in Immunology to Oncology
Karoly Szuhai et al.
CLINICAL CANCER RESEARCH (2009)
GLI1 Is a Direct Transcriptional Target of EWS-FLI1 Oncoprotein
Elspeth Beauchamp et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Phase I, Pharmacokinetic, and Pharmacodynamic Study of AMG 479, a Fully Human Monoclonal Antibody to Insulin-Like Growth Factor Receptor 1
Anthony W. Tolcher et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
Peripheral Primitive Neuroectodermal Tumour in a Lumbar Vertebra and the Liver of a Dromedary Camel (Camelus dromedarius)
R. Weiss et al.
JOURNAL OF COMPARATIVE PATHOLOGY (2009)
A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma
Hayriye V. Erkizan et al.
NATURE MEDICINE (2009)
GSTM4 is a microsatellite-containing EWS/FLI target involved in Ewing's sarcoma oncogenesis and therapeutic resistance
W. Luo et al.
ONCOGENE (2009)
O-GlcNAcylation is involved in the transcriptional activity of EWS-FLI1 in Ewing's sarcoma
R. Bachmaier et al.
ONCOGENE (2009)
The Oncogenic EWS-FLI1 Protein Binds In Vivo GGAA Microsatellite Sequences with Potential Transcriptional Activation Function (Publication with Expression of Concern. See vol. 17, 2022)
Noelle Guillon et al.
PLOS ONE (2009)
A Molecular Function Map of Ewing's Sarcoma
Maximilian Kauer et al.
PLOS ONE (2009)
GLI1 Is a Central Mediator of EWS/FLI1 Signaling in Ewing Tumors
Jay Joo et al.
PLOS ONE (2009)
Phase II Study of Intermediate-Dose Cytarabine in Patients With Relapsed or Refractory Ewing Sarcoma: A Report From the Children's Oncology Group
Steven G. DuBois et al.
PEDIATRIC BLOOD & CANCER (2009)
Initial Testing (Stage 1) of Vorinostat (SAHA) by the Pediatric Preclinical Testing Program
Nino Keshelava et al.
PEDIATRIC BLOOD & CANCER (2009)
EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation
Guenther H. S. Richter et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Development of IGF-IR Inhibitors in Pediatric Sarcomas
E. Anders Kolb et al.
CURRENT ONCOLOGY REPORTS (2009)
EWS-FLI1 suppresses NOTCH-activated p53 in Ewing's sarcoma
Jozef Ban et al.
CANCER RESEARCH (2008)
EWS-FLI-1 expression triggers a Ewing's sarcoma initiation program in primary human mesenchymal stem cells
Nicolo Riggi et al.
CANCER RESEARCH (2008)
A transcriptional profiling meta-analysis reveals a core EWS-FLI gene expression signature
Jeffrey D. Hancock et al.
CELL CYCLE (2008)
POU5F1, encoding a key regulator of stem cell pluripotency, is fused to EWSR1 in hidradenoma of the skin and mucoepidermoid carcinoma of the salivary glands
E. Moller et al.
JOURNAL OF PATHOLOGY (2008)
DAX1, a direct target of EWS/FLI1 oncoprotein, is a principal regulator of cell-cycle progression in Ewing's tumor cells
E. Garcia-Aragoncillo et al.
ONCOGENE (2008)
EWS/FLI Mediates Transcriptional Repression via NKX2.2 during Oncogenic Transformation in Ewing's Sarcoma
Leah A. Owen et al.
PLOS ONE (2008)
IGF1 Is a Common Target Gene of Ewing's Sarcoma Fusion Proteins in Mesenchymal Progenitor Cells
Luisa Cironi et al.
PLOS ONE (2008)
Microsatellites as EWIS/FLI response elements in Ewing's sarcoma
Kunal Gangwal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The EWS/FLI1 oncogenic transcription factor deregulates GLI1
J. P. Zwerner et al.
ONCOGENE (2008)
Undifferentiated small round cell sarcomas with rare EWS gene fusions -: Identification of a novel EWS-SP3 fusion and of additional cases with the EWS-ETV1 and EWS-FEV Fusions
Lu Wang et al.
JOURNAL OF MOLECULAR DIAGNOSTICS (2007)
Mesenchymal stem cell features of Ewing tumors
Franck Tirode et al.
CANCER CELL (2007)
Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcoma
Kimberly Stegmaier et al.
PLOS MEDICINE (2007)
Nkx2.2-repressor activity is sufficient to specify α-cells and a small number of β-cells in the pancreatic islet
Michelle J. Doyle et al.
DEVELOPMENT (2007)
Ewing sarcoma with novel translocation t(2;16) producing an in-frame fusion of FUS and FEV
Tony L. Ng et al.
JOURNAL OF MOLECULAR DIAGNOSTICS (2007)
Sarcomas: genetics, signalling, and cellular origins. Part I: The fellowship of TET
N. Riggi et al.
JOURNAL OF PATHOLOGY (2007)
Expression of EWS-ETS fusions in NIH3T3 cells reveals significant differences to Ewing's sarcoma
Chi L. Braunreiter et al.
CELL CYCLE (2006)
NR0B1 is required for the oncogenic phenotype mediated by EWS/FLI in Ewing's sarcoma
Michelle Kinsey et al.
MOLECULAR CANCER RESEARCH (2006)
Identification of target genes in their native cellular context - An analysis of EWS/FLI in Ewing's sarcoma
Leah A. Owen et al.
CELL CYCLE (2006)
Insulin-like growth factor binding protein 3 as an anticancer molecule in Ewing's sarcoma
Stefania Benini et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
Oncoprotein EWS-FLI1 activity is enhanced by RNA helicase A
Jeffrey A. Toretsky et al.
CANCER RESEARCH (2006)
Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma
Richard Smith et al.
CANCER CELL (2006)
Development of Ewing's sarcoma from primary bone marrow-derived mesenchymal progenitor cells
N Riggi et al.
CANCER RESEARCH (2005)
Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma
S Hu-Lieskovan et al.
CANCER RESEARCH (2005)
EWSR1 is fused to POU5F1 in a bone tumor with translocation t(6;22)(p21;q12)
S Yamaguchi et al.
GENES CHROMOSOMES & CANCER (2005)
EWS-FLI1 fusion protein up-regulates critical genes in neural crest development and is responsible for the observed phenotype of Ewing's family of tumors
S Hu-Lieskovan et al.
CANCER RESEARCH (2005)
Ewing sarcomas with p53 mutation or p16/p14ARF homozygous deletion:: A highly lethal subset associated with poor chemoresponse
HY Huang et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
The coactivator LXXLL nuclear receptor recognition motif
RS Savkur et al.
JOURNAL OF PEPTIDE RESEARCH (2004)
The Ews/Fli-1 fusion gene switches the differentiation program of neuroblastomas to ewing sarcoma/peripheral primitive neuroectodermal tumors
CJ Rorie et al.
CANCER RESEARCH (2004)
Role of protein-protein interactions in the antiapoptotic function of EWS-Fli-1
R Ramakrishnan et al.
ONCOGENE (2004)
EWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3
A Prieur et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Targeting of EWS/FLI-1 by RNA interference attenuates the tumor phenotype of Ewing's sarcoma cells in vitro
HA Chansky et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2004)
Potentials for RNAi in sarcoma research and therapy: Ewing's sarcoma as a model
H Kovar et al.
SEMINARS IN CANCER BIOLOGY (2003)
PIM3 proto-oncogene kinase is a common transcriptional target of divergent EWS/IETS oncoproteins
B Deneen et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Beta-platelet-derived growth factor receptor mediates motility and growth of Ewing's sarcoma cells
A Üren et al.
ONCOGENE (2003)
Downregulation of c-Jun expression and cell cycle regulatory molecules in acute myeloid leukemia cells upon CD44 ligation
AAP Zada et al.
ONCOGENE (2003)
Alteration of mesodermal cell differentiation by EWS/FLI-1, the oncogene implicated in Ewing's sarcoma
S Eliazer et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts
SL Lessnick et al.
CANCER CELL (2002)
Biology of EWS/ETS fusions in Ewing's family tumors
A Arvand et al.
ONCOGENE (2001)
PDGF-C is an EWS/FLI induced transforming growth factor in Ewing family tumors
JP Zwerner et al.
ONCOGENE (2001)
The role of Fli-1 in normal cell function and malignant transformation
AHL Truong et al.
ONCOGENE (2000)