期刊
ANNUAL REVIEW OF NEUROSCIENCE, VOL 34
卷 34, 期 -, 页码 389-412出版社
ANNUAL REVIEWS
DOI: 10.1146/annurev-neuro-061010-113817
关键词
channelrhodopsin; halorhodopsin; bacteriorhodopsin; electrophysiology
资金
- NATIONAL INSTITUTE OF MENTAL HEALTH [R01MH086373, R01MH075957] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON DRUG ABUSE [R01DA020794] Funding Source: NIH RePORTER
- OFFICE OF THE DIRECTOR, NATIONAL INSTITUTES OF HEALTH [DP1OD000616] Funding Source: NIH RePORTER
- NIDA NIH HHS [R01 DA020794, R01 DA020794-01] Funding Source: Medline
- NIH HHS [DP1 OD000616-01, DP1 OD000616] Funding Source: Medline
- NIMH NIH HHS [R01 MH075957-01A2, R01 MH086373-01, R01 MH075957, R01 MH086373] Funding Source: Medline
Genetically encoded, single-component optogenetic tools have made a significant impact on neuroscience, enabling specific modulation of selected cells within complex neural tissues. As the optogenetic toolbox contents grow and diversify, the opportunities for neuroscience continue to grow. In this review, we outline the development of currently available single-component optogenetic tools and summarize the application of various optogenetic tools in diverse model organisms.
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