期刊
ANNUAL REVIEW OF NEUROSCIENCE
卷 31, 期 -, 页码 479-509出版社
ANNUAL REVIEWS
DOI: 10.1146/annurev.neuro.31.060407.125533
关键词
synaptogenesis; activity-dependent; visual plasticity; axonal refinement; retinal waves; axon guidance
资金
- NATIONAL EYE INSTITUTE [R01EY013528, R01EY011369] Funding Source: NIH RePORTER
- NEI NIH HHS [R01 EY013528, R01 EY011369, R01 EY013528-09, R01 EY13528, R01 EY011369-11, EY11369] Funding Source: Medline
Patterns of synaptic connections in the visual system are remarkably precise. These connections dictate the receptive field properties of individual visual neurons and ultimately determine the quality of visual perception. Spontaneous neural activity is necessary for the development of various receptive field properties and visual feature maps. In recent years, attention has shifted to understanding the mechanisms by which spontaneous activity in the developing retina, lateral geniculate nucleus, and visual cortex instruct the axonal and dendritic refinements that give rise to orderly connections in the visual system. Axon guidance cues and a growing list of other molecules, including immune system factors, hive also recently been implicated in visual circuit wiring. A major goal now is to determine how these molecules cooperate with spontaneous and visually evoked activity to give rise to the circuits underlying precise receptive field tuning and orderly Visual maps.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据