期刊
ANNUAL REVIEW OF MICROBIOLOGY, VOL 64, 2010
卷 64, 期 -, 页码 223-240出版社
ANNUAL REVIEWS
DOI: 10.1146/annurev.micro.112408.134102
关键词
cell division; cell length; cell diameter; bacterial cytoskeleton; MreB; FtsZ
类别
资金
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM061019] Funding Source: NIH RePORTER
- NIGMS NIH HHS [R01-GM061019, R01 GM061019] Funding Source: Medline
Events in the past decide h we made it both possible and interesting to ask how bacteria create cells of defined length, diameter, and morphology The current consensus is that bacterial shape is determined by the coordinated activities of cytoskeleton complexes that drive cell elongation and division Cell length is most easily explained by the timing of cell division, principally by regulating the activity of the FtsZ protein However, the question of how cells establish and maintain a specific and uniform diameter is, by fir, much more difficult to answer Mutations associated with the elongation complex often alter cell width, though it is not clear how Some evidence suggests that diameter is strongly influenced by events during cell division In addition, surprising new observations show that the bacterial cell wall is more highly malleable than previously believed and that cells can alter and restore their shapes by relying only on internal mechanisms
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