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IL-12 is required for anti-OX40-mediated CD4 T cell survival
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OX40 Costimulatory Signals Potentiate the Memory Commitment of Effector CD8+ T Cells
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In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation
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Defects in the acquisition of CD8 T cell effector function after priming with tumor or soluble antigen can be overcome by the addition of an OX40 agonist
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JOURNAL OF IMMUNOLOGY (2007)
OX40 ligand expressed by DCs costimulates NKT and CD4+ Th cell antitumor immunity in mice
Jamal Zaini et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Differential requirements for OX40 signals on generation of effector and central memory CD4+ T cells
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OX40 controls functionally different T cell subsets and their resistance to depletion therapy
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JOURNAL OF IMMUNOLOGY (2007)
OX40 costimulation promotes persistence of cytomegalovirus-specific CD8 T cells: A CD4-dependent mechanism
Ian R. Humphreys et al.
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JOURNAL OF IMMUNOLOGY (2007)
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JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Cooperation between CD4 and CD8 T cells for anti-tumor activity is enhanced by OX40 signals
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EUROPEAN JOURNAL OF IMMUNOLOGY (2007)
Development and characterization of recombinant human Fc:OX40L fusion protein linked via a coiled-coil trimerization domain
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MOLECULAR IMMUNOLOGY (2007)
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JOURNAL OF GENE MEDICINE (2007)
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NATURE IMMUNOLOGY (2007)
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JOURNAL OF IMMUNOLOGY (2006)
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IMMUNOLOGY LETTERS (2006)
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OX40-OX40 ligand interaction through T cell-T cell contact contributes to CD4 T cell longevity
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OX40 Ligation of CD4+ T cells enhances virus-specific CD8+ T cell memory responses independently of IL-2 and CD4+ T regulatory cell inhibition
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JOURNAL OF IMMUNOLOGY (2006)
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OX40 costimulation synergizes with GM-CSF whole-cell vaccination to overcome established CD8+ T cell tolerance to an endogenous tumor antigen
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JOURNAL OF IMMUNOLOGY (2006)
Coexpression of CD25 and OX40 (CD134) receptors delineates autoreactive T-cells in type 1 diabetes
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OX40 interactions in gastrointestinal nematode infection
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IMMUNOLOGY (2006)
Evaluation of OX40 ligand as a costimulator of human antiviral memory CD8 T cell responses: Comparison with B7.1 and 4-1BBL
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JOURNAL OF IMMUNOLOGY (2005)
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OX40 and Bcl-XL promote the persistence of CD8 T cells to recall tumor-associated antigen
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JOURNAL OF IMMUNOLOGY (2005)
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Endothelial cell co-stimulation through OX40 augments and prolongs T cell cytokine synthesis by stabilization of cytokine mRNA
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OX40 ligand and CD30 ligand are expressed on adult but not neonatal CD4+CD3- inducer cells:: Evidence that IL-7 signals regulate CD30 ligand but not OX40 ligand expression
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Sustained survivin expression from OX40 costimulatory signals drives T cell clonal expansion
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Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility
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Triggering of OX40 (CD134) on CD4+CD25+ T cells blocks their inhibitory activity:: a novel regulatory role for OX40 and its comparison with GITR
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BLOOD (2005)
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Plasmacytoid dendritic cells regulate Th cell responses through OX40 ligand and type IIFNs
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Use of CD134 as a primary receptor by the feline immunodeficiency virus
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NATURE IMMUNOLOGY (2004)
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4-1BB and OX40 dual costimulation synergistically stimulate primary specific CD8 T cells for robust effector function
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Selective maturation of dendritic cells by Nippostrongylus brasiliensis-secreted proteins drives Th2 immune responses
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OX40 (CD134) controls memory T helper 2 cells that drive lung inflammation
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OX40 Ligation on activated T cells enhances the control of Cryptococcus neoformans and reduces pulmonary eosinophilia
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JOURNAL OF IMMUNOLOGY (2003)
Costimulation through OX40 is crucial for induction of an alloreactive human T-cell response
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IMMUNOLOGY (2003)
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CD4+CD3- accessory cells costimulate primed CD4 T cells through OX40 and CD30 at sites where T cells collaborate with B cells
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IMMUNITY (2003)
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JOURNAL OF IMMUNOLOGY (2003)
OX40-mediated memory T cell generation is TNF receptor-associated factor 2 dependent
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JOURNAL OF IMMUNOLOGY (2003)
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IMMUNOLOGY LETTERS (2002)
Constitutive OX40/OX40 ligand interaction induces autoimmune-like diseases
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JOURNAL OF IMMUNOLOGY (2002)
Ox40 costimulation enhances the development of T cell responses induced by dendritic cells in vivo
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JOURNAL OF IMMUNOLOGY (2002)
OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells
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IMMUNITY (2001)
Critical involvement of OX40 ligand signals in the T cell priming events during experimental autoimmune encephalomyelitis
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JOURNAL OF IMMUNOLOGY (2001)
Signaling through OX40 (CD134) breaks peripheral T-cell tolerance
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NATURE MEDICINE (2001)
Expression of gp34 (OX40 ligand) and OX40 on human T cell clones
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JAPANESE JOURNAL OF CANCER RESEARCH (2001)
The OX40 costimulatory receptor determines the development of CD4 memory by regulating primary clonal expansion
I Gramaglia et al.
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Human monocyte-derived dendritic cells induce naive T cell differentiation into T helper cell type 2 (Th2) or Th1/Th2 effectors: Role of stimulator/responder ratio
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CD28, Ox-40, LFA-1, and CD4 modulation of Th1/Th2 differentiation is directly dependent on the dose of antigen
PR Rogers et al.
JOURNAL OF IMMUNOLOGY (2000)
Engagement of the OX-40 receptor in vivo enhances antitumor immunity
AD Weinberg et al.
JOURNAL OF IMMUNOLOGY (2000)
Critical contribution of OX40 ligand to T helper cell type 2 differentiation in experimental leishmaniasis
H Akiba et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Impairment of antigen-presenting cell function in mice lacking expression of OX40 ligand
K Murata et al.
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Danger and OX40 receptor signaling synergize to enhance memory T cell survival by inhibiting peripheral deletion
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