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EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2008)
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Non-IgE-mediated chronic allergic skin inflammation revealed with rBet v 1 fragments
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The European Union CREATE Project: A model for international standardization of allergy diagnostics and vaccines
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Several distinct properties of the IgE repertoire determine effector cell degranulation in response to allergen challenge
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Intranasal immunization with a dominant T-cell epitope peptide of a major allergen of olive pollen prevents mice from sensitization to the whole allergen
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The IgE repertoire in PBMCs of atopic patients is characterized by individual rearrangements without variable region of the heavy immunoglobulin chain bias
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Allergy multivaccines created by DNA shuffling of tree pollen allergens
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Induction of ovalbumin-specific tolerance by oral administration of Lactococcus lactis secreting ovalbumin
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Exposure to a farming environment has allergen-specific protective effects on TH2-dependent isotype switching in response to common inhalants
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NATURE REVIEWS IMMUNOLOGY (2006)
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Der p 1 peptide on virus-like particles is safe and highly immunogenic in healthy adults
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Molecular design of allergy vaccines
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Regulatory activity of human CD4+ CD25+ T cells depends on allergen concentration, type of allergen and atopy status of the donor
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Allergen-specific nasal IgG antibodies induced by vaccination with genetically modified allergens are associated with reduced nasal allergen sensitivity
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Development of an in vitro system for the study of allergens and allergen-specific immunoglobulin E and immunoglobulin G:: Fcε receptor I supercross-linking is a possible new mechanism of immunoglobulin G-dependent enhancement of type I allergic reactions
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A hybrid molecule resembling the epitope spectrum of grass pollen for allergy vaccination
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A chimeric human-cat fusion protein blocks cat-induced allergy
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T cell epitope immunotherapy induces a CD4+ T cell population with regulatory activity
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Importance of databases in experimental and clinical allergology
A Mari
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Fel d 1-derived T cell peptide therapy induces recruitment of CD4(+)CD25(+); CD4(+) interferon-gamma(+) T helper type 1 cells to sites of allergen-induced late-phase skin reactions in cat-allergic subjects
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PEDIATRIC ALLERGY AND IMMUNOLOGY (2004)
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VH gene usage in immunoglobulin E responses of seasonal rhinitis patients allergic to grass pollen is oligoclonal and antigen driven
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CLINICAL AND EXPERIMENTAL ALLERGY (2004)
Amb a 1-immunostimulatory oligodeoxynucleotide conjugate immunotherapy decreases the nasal inflammatory response
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Non-anaphylactic surface-exposed peptides of the major birch pollen allergen, Bet v 1, for preventive vaccination
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Genetically engineered negative signaling molecules in the immunomodulation of allergic diseases
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MR Karlsson et al.
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Late asthmatic reactions induced by inhalation of allergen-derived T cell peptides
FR Ali et al.
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Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells
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A novel approach to specific allergy treatment:: The recombinant fusion protein of a bacterial cell surface (S-layer) protein and the major birch pollen allergen Bet v 1 (rSbsC-Bet v 1) combines reduced allergenicity with immunomodulating capacity
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Vaccination with genetically engineered allergens prevents progression of allergic disease
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Cat allergen peptide immunotherapy reduces CD4+ T cell responses to cat allergen but does not alter suppression by CD4+ CD25+ T cells:: a double-blind placebo-controlled study
TRF Smith et al.
ALLERGY (2004)
Generation of an allergy vaccine by disruption of the three-dimensional structure of the cross-reactive calcium-binding allergen, Phl p 7
K Westritschnig et al.
JOURNAL OF IMMUNOLOGY (2004)
Formation of disulfide bonds and homodimers of the major cat allergen Fel d 1 equivalent to the natural allergen by expression in Escherichia coli
H Grönlund et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Allergen-specific immunotherapy with a monophosphoryl lipid A-adjuvanted vaccine: reduced seasonally boosted immunoglobulin E production and inhibition of basophil histamine release by therapy-induced blocking antibodies
N Mothes et al.
CLINICAL AND EXPERIMENTAL ALLERGY (2003)
Renaissance of the blocking antibody concept in type I allergy
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INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY (2003)
Prevention of allergen-specific IgE production and suppression of an established Th2-type response by immunization with DNA encoding hypoallergenic allergen derivatives of Bet v 1, the major birch-pollen allergen
R Hochreiter et al.
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Oral administration of specific antigens to allergy-prone infant dogs induces IL-10 and TGF-β expression and prevents allergy in adult life
B Zemann et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2003)
Human CD4+CD25+ T cells derived from the majority of atopic donors are able to suppress TH1 and TH2 cytokine production
I Bellinghausen et al.
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Allergen-specific T-cell tolerance induction with allergen-derived long synthetic peptides: Results of a phase I trial
JM Fellrath et al.
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Stem cells engineered to express self-antigen to treat autoimmunity
F Alderuccio et al.
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Microarrayed recombinant allergens for diagnosis of allergy
C Harwanegg et al.
CLINICAL AND EXPERIMENTAL ALLERGY (2003)
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A Horst et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2002)
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R van Ree
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Environmental exposure to endotoxin and its relation to asthma in school-age children
C Braun-Fahrländer et al.
NEW ENGLAND JOURNAL OF MEDICINE (2002)
Gene gun bombardment with gold particles displays a particular Th2-promoting signal that over-rules the Th1-inducing effect of immunostimulatory CpG motifs in DNA vaccines
R Weiss et al.
VACCINE (2002)
Effect of T-cell peptides derived from Fel d 1 on allergic reactions and cytokine production in patients sensitive to cats:: a randomised controlled trial
WLG Oldfield et al.
LANCET (2002)
Pollen immunotherapy reduces the development of asthma in children with seasonal rhinoconjunctivitis (the PAT-Study)
C Möller et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2002)
Inhibition of mucosal and systemic Th2-type immune responses by intranasal peptides containing a dominant T cell epitope of the allergen Der p 1
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Intranasal treatment with a recombinant hypoallergenic derivative of the major birch pollen allergen Bet v 1 prevents allergic sensitization and airway inflammation in mice
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INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY (2001)
Late asthmatic reactions provoked by intradermal injection of T-cell peptide epitopes are not associated with bronchial mucosal infiltration of eosinophils or TH2-type cells or with elevated concentrations of histamine or eicosanoids in bronchoalveolar fluid
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2001)
Allergen-derived T cell peptide-induced late asthmatic reactions precede the induction of antigen-specific hyporesponsiveness in atopic allergic asthmatic subjects
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JOURNAL OF IMMUNOLOGY (2001)
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C Suphioglu et al.
FEBS LETTERS (2001)
Monomeric IgE stimulates signaling pathways in mast cells that lead to cytokine production and cell survival
J Kalesnikoff et al.
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T cell epitope-containing hypoallergenic recombinant fragments of the major birch pollen allergen, Bet v 1, induce blocking antibodies
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2000)
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N Katoh et al.
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S Korematsu et al.
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