相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Direct evidence of a heterotrimeric complex of human interleukin-4 with its receptors
Ross C. Hoffman et al.
PROTEIN SCIENCE (2010)
The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation
Guido Hansen et al.
CELL (2008)
Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system
Sherry L. LaPorte et al.
CELL (2008)
Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Rα, IL-13Rα1, and γc regulates relative cytokine sensitivity
Ilkka S. Junttila et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Structural organization of a full-length gp130/LIF-R cytokine receptor transmembrane complex
Georgios Skiniotis et al.
MOLECULAR CELL (2008)
Crystal structure of the interleukin-15•interleukin-15 receptor α complex -: Insights into trans and cis presentation
Shaun K. Olsen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Crystal structure of the IL-15-IL-15Rα complex, a cytokine-receptor unit presented in trans
Mami Chirifu et al.
NATURE IMMUNOLOGY (2007)
Elucidation of the interleukin-15 binding site on its alpha receptor by NMR
Nicole A. Hanick et al.
BIOCHEMISTRY (2007)
An unusual cytokine: Ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (LIF) in complex with the LIF receptor
Trevor Huyton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
JAK-STAT signaling: From interferons to cytokines
Christian Schindler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
The dynamics of signal triggering in a gp130-receptor complex
Rishi Matadeen et al.
STRUCTURE (2007)
The JAK-STAT signaling pathway: Input and output intergration
Peter J. Murray
JOURNAL OF IMMUNOLOGY (2007)
Hot-spot mimicry of a cytokine receptor by a small molecule
Christopher D. Thanos et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
IL-15/IL-15 receptor biology: A guided tour through an expanding universe
Vadirn Budagian et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2006)
The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design
Thomas A. Waldmann
NATURE REVIEWS IMMUNOLOGY (2006)
IL-4 receptor α is an important modulator of IL-4 and IL-13 receptor binding:: Implications for the development of therapeutic targets
Allison-Lynn Andrews et al.
JOURNAL OF IMMUNOLOGY (2006)
The structure of the interleukin-15α receptor and its implications for ligand binding
I Lorenzen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Homodimeric cross-over structure of the human granulocyte colony-stimulating factor (GCSF) receptor signaling complex
T Tamada et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Crystal structure of the IL-2 signaling complex: Paradigm for a heterotrimeric cytokine receptor
DJ Stauber et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor
IS Lucet et al.
BLOOD (2006)
Structure of the quaternary complex of interleukin-2 with its α, β, and γc receptors
XQ Wang et al.
SCIENCE (2005)
Crystal structure of the Jak3 kinase domain in complex with a staurosporine analog
TJ Boggon et al.
BLOOD (2005)
Characterization of the interaction between interleukin-13 and interleukin-13 receptors
K Arima et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The structure of interleukin-2 complexed with its alpha receptor
M Rickert et al.
SCIENCE (2005)
Signaling conformations of the tall cytokine receptor gp130 when in complex with IL-6 and IL-6 receptor
G Skiniotis et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)
Structural bases of unphosphorylated STAT1 association and receptor binding
X Mao et al.
MOLECULAR CELL (2005)
WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27
S Pflanz et al.
JOURNAL OF IMMUNOLOGY (2004)
The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain
RP Donnelly et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2004)
IL-2 and IL-15 receptor α-subunits are coexpressed in a supramolecular receptor cluster in lipid rafts of T cells
G Vámosi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Cytokines and immunodeficiency diseases:: critical roles of the γc-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their signaling pathways
PE Kovanen et al.
IMMUNOLOGICAL REVIEWS (2004)
Compensatory energetic mechanisms mediating the assembly of signaling complexes between interleukin-2 and its α, β, and γc receptors
M Rickert et al.
JOURNAL OF MOLECULAR BIOLOGY (2004)
Convergent mechanisms for recognition of divergent cytokines by the shared signaling receptor gp130
MJ Boulanger et al.
MOLECULAR CELL (2003)
Principles of interleukin (IL)-6-type cytokine signalling and its regulation
PC Heinrich et al.
BIOCHEMICAL JOURNAL (2003)
Molecular phylogeny within type I cytokines and their cognate receptors
JL Boulay et al.
IMMUNITY (2003)
Hexameric structure and assembly of the interleukin-6/IL-6 α-receptor/gp130 complex
MJ Boulanger et al.
SCIENCE (2003)
A novel functional epitope formed by domains 1 and 4 of the human common β-subunit is involved in receptor activation by granulocyte macrophage colony-stimulating factor and interleukin 5
JM Murphy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Binding of small molecules to an adaptive protein-protein interface
MR Arkin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Human IL-21 and IL-4 bind to partially overlapping epitopes of common γ-chain
JL Zhang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Thermodynamic analysis of degenerate recognition by the NKG2D immunoreceptor: Not induced fit but rigid adaptation
BJ McFarland et al.
IMMUNITY (2003)
Structure of the extracellular domains of the human interleukin-6 receptor α-chain
JN Varghese et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Structure, binding, and antagonists in the IL-4/IL-13 receptor system
TD Mueller et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2002)
IL-15Rα recycles and presents IL-15 in trans to neighboring cells
S Dubois et al.
IMMUNITY (2002)
The neurotrophin receptor p75NTR:: novel functions and implications for diseases of the nervous system
G Dechant et al.
NATURE NEUROSCIENCE (2002)
STATs: Transcriptional control and biological impact
DE Levy et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
Cytokine and cytokine receptor pleiotropy and redundancy
K Ozaki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
IL-27, a heterodimeric cytokine composed of EB13 and p28 protein, induces proliferation of naive CD4+ T cells
S Pflanz et al.
IMMUNITY (2002)
A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rβ1 and a novel cytokine receptor subunit, IL-23R
C Parham et al.
JOURNAL OF IMMUNOLOGY (2002)
Identification of amino acid residues of gp130 signal transducer and gp80 α receptor subunit that are involved in ligand binding and signaling by human herpesvirus 8-encoded interleukin-6
H Li et al.
JOURNAL OF VIROLOGY (2002)
Asymmetric ligand recognition by the activating natural killer cell receptor NKG2D, a symmetric homodimer
RK Strong
MOLECULAR IMMUNOLOGY (2002)
The GDNF family: Signalling, biological functions and therapeutic value
MS Airaksinen et al.
NATURE REVIEWS NEUROSCIENCE (2002)
Structural basis for binding multiple ligands by the common cytokine receptor γ-chain
F Olosz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Analysis of the role of the interleukin-2 receptor γ chain in ligand binding
SF Liparoto et al.
BIOCHEMISTRY (2002)
The high-affinity interaction of human IL-4 and the receptor α chain is constituted by two independent binding clusters
JL Zhang et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
Functional epitope of common gamma chain for interleukin-4 binding
JL Zhang et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2002)
Cytokines and immunodeficiency diseases
WJ Leonard
NATURE REVIEWS IMMUNOLOGY (2001)
Identification of ligand-binding site III on the immunoglobulin-like domain of the granulocyte colony-stimulating factor receptor
JE Layton et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
In vitro reconstitution of recognition and activation complexes between interleukin-6 and gp130
DC Chow et al.
BIOCHEMISTRY (2001)
The Stat family in cytokine signaling
JN Ihle
CURRENT OPINION IN CELL BIOLOGY (2001)
Structure of an extracellular gp130 cytokine receptor signaling complex
DC Chow et al.
SCIENCE (2001)
Structure of the complete extracellular domain of the common β subunit of the human GM-CSF, IL-3, and IL-5 receptors reveals a novel dimer configuration
PD Carr et al.
CELL (2001)
A T-cell-selective interleukin 2 mutein exhibits potent antitumor activity and is well tolerated in vivo
AB Shanafelt et al.
NATURE BIOTECHNOLOGY (2000)
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
B Oppmann et al.
IMMUNITY (2000)
Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: Formation of a functional heteromeric complex requires interleukin 7 receptor
LS Park et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex
GCA Elson et al.
NATURE NEUROSCIENCE (2000)
Crystal structure and functional dissection of the cytostatic cytokine oncostatin M
MC Deller et al.
STRUCTURE WITH FOLDING & DESIGN (2000)
Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen.
AMJ Shapiro et al.
NEW ENGLAND JOURNAL OF MEDICINE (2000)
Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12
C Yoon et al.
EMBO JOURNAL (2000)
Cloning of a receptor subunit required for signaling by thymic stromal lymphopoietin
A Pandey et al.
NATURE IMMUNOLOGY (2000)
Receptor recognition by gp130 cytokines
J Bravo et al.
EMBO JOURNAL (2000)
Human herpes virus 8 interleukin-6 homologue triggers gp130 on neuronal and hematopoietic cells
SH Hoischen et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2000)
The safety and efficacy of a two-dose daclizumab (zenapax) induction therapy in liver transplant recipients
DE Eckhoff et al.
TRANSPLANTATION (2000)
Prevention of rejection in cardiac transplantation by blockade of the interleukin-2 receptor with a monoclonal antibody.
A Beniaminovitz et al.
NEW ENGLAND JOURNAL OF MEDICINE (2000)