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Jason D. Fontenot et al.
JOURNAL OF IMMUNOLOGY (2017)
Associations between the PTPN22 1858C→T polymorphism and radiographic joint destruction in patients with rheumatoid arthritis:: results from a 10-year longitudinal study
Benedicte A. Lie et al.
ANNALS OF THE RHEUMATIC DISEASES (2007)
B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity
Lily I. Pao et al.
IMMUNITY (2007)
Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases
D. M. Owens et al.
ONCOGENE (2007)
Investigation of genetic variation across the protein tyrosine phosphatase gene in patients with rheumatoid arthritis in the UK
Anne Hinks et al.
ANNALS OF THE RHEUMATIC DISEASES (2007)
No independent role of the -1123 G>C and +2740 A>G variants in the association of PTPN22 with type 1 diabetes and juvenile idiopathic arthritis in two Caucasian populations
Ondrej Cinek et al.
DIABETES RESEARCH AND CLINICAL PRACTICE (2007)
miR-181a is an intrinsic modulator of T cell sensitivity and selection
Qi-Jing Li et al.
CELL (2007)
The 620W allele is the PTPN22 genetic variant conferring susceptibility to RA in a Dutch population
J. Wesoly et al.
RHEUMATOLOGY (2007)
Normal TCR signal transduction in mice that lack catalytically active PTPN3 protein tyrosine phosphatase
Timothy J. Bauler et al.
JOURNAL OF IMMUNOLOGY (2007)
Foxp3 occupancy and regulation of key target genes during T-cell stimulation
Alexander Marson et al.
NATURE (2007)
Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
Yan Zheng et al.
NATURE (2007)
Autoimmunity and atherosclerosis:: functional polymorphism of PTPN22 is associated with phenotypes related to the risk of atherosclerosis.: The Cardiovascular Risk in Young Finns Study
M. Pertovaara et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2007)
The role of Shp2 (PTPN11) in cancer
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CURRENT OPINION IN GENETICS & DEVELOPMENT (2007)
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
Jeong M. Kim et al.
NATURE IMMUNOLOGY (2007)
PTPN11 is the first identified proto-oncogene that encodes a tyrosine phosphatase
Rebecca J. Chan et al.
BLOOD (2007)
The PTPN22 C1858T functional polymorphism and autoimmune diseases - a meta-analysis
Y. H. Lee et al.
RHEUMATOLOGY (2007)
MAPK phosphatases - regulating the immune response
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NATURE REVIEWS IMMUNOLOGY (2007)
Dual-specificity phosphatase 1: a critical regulator of innate immune responses
S. M. Abraham et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2006)
Conditional deletion of Shp2 tyrosine phosphatase in thymocytes suppresses both pre-TCR and TCR signals
Thanh V. Nguyen et al.
JOURNAL OF IMMUNOLOGY (2006)
Haplotype analysis revealed no association between the PTPN22 gene and RA in a Japanese population
K. Ikari et al.
RHEUMATOLOGY (2006)
A haplotype-based analysis of the PTPN22 locus in type 1 diabetes
Suna Onengut-Gumuscu et al.
DIABETES (2006)
Regulation of MAP kinases by the VHR dual-specific phosphatase - Implications for cell growth and differentiation
Fabio Cerignoli et al.
CELL CYCLE (2006)
Dual specificity phosphotase 18, interacting with SAPK, dephosphorylates SAPK and inhibits SAPK/JNK signal pathway in vivo
Qihan Wu et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2006)
Role of PTPN22 in type 1 diabetes and other autoimmune diseases
Nunzio Bottini et al.
SEMINARS IN IMMUNOLOGY (2006)
Spontaneous development of autoimmune arthritis due to genetic anomaly of T cell signal transduction: Part 1
Shimon Sakaguchi et al.
SEMINARS IN IMMUNOLOGY (2006)
Evidence for susceptibility determinant(s) to psoriasis vulgaris in or near PTPN22 in German patients
U. Hueffmeier et al.
JOURNAL OF MEDICAL GENETICS (2006)
Lymphoid tyrosine phosphatase (LYP/PTPN22) Arg620Trp variant regulates insulin autoimmunity and progression to type 1 diabetes
R Hermann et al.
DIABETOLOGIA (2006)
CD2BP1 modulates CD2-dependent T cell activation via linkage to protein tyrosine phosphatase (PTP)-PEST
Hailin Yang et al.
JOURNAL OF IMMUNOLOGY (2006)
The PTPN22 1858T variant is not associated with primary biliary cirrhosis
P Milkiewicz et al.
TISSUE ANTIGENS (2006)
The 1858T PTPN22 gene variant contributes to a genetic risk of type 1 diabetes in a Ukrainian population
M Fedetz et al.
TISSUE ANTIGENS (2006)
PTPN22 and invasive bacterial disease
SJ Chapman et al.
NATURE GENETICS (2006)
Identification of substrates of human protein-tyrosine phosphatase PTPN22
JS Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Systematic search for single nucleotide polymorphisms in a lymphoid tyrosine phosphatase gene (PTPN22):: Association between a promoter polymorphism and type I diabetes in Asian populations
E Kawasaki et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2006)
PTPN11 (Shp2) mutations in LEOPARD syndrome have dominant negative, not activating, effects
MI Kontaridis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Positive regulation of immune cell function and inflammatory responses by phosphatase PAC-1
KL Jeffrey et al.
NATURE IMMUNOLOGY (2006)
Association of the PTPN22*R620W polymorphism with autoimmune myasthenia gravis
C Vandiedonck et al.
ANNALS OF NEUROLOGY (2006)
The dual specificity phosphatase transcriptome of the murine thymus
MB Tanzola et al.
MOLECULAR IMMUNOLOGY (2006)
Targeting the PTPome in human disease
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EXPERT OPINION ON THERAPEUTIC TARGETS (2006)
Molecular signature of mice T lymphocytes following tolerance induction by allogeneic BMT and CD40-CD40L costimulation blockade
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TRANSPLANT INTERNATIONAL (2006)
CD45 links the B cell receptor with cell survival and is required for the persistence of germinal centers
ND Huntington et al.
NATURE IMMUNOLOGY (2006)
PTPN22 polymorphism and anti-cyclic citrullinated peptide antibodies in combination strongly predicts future onset of rheumatoid arthritis and has a specificity of 100% for the disease
M Johansson et al.
ARTHRITIS RESEARCH & THERAPY (2006)
Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant
T Vang et al.
NATURE GENETICS (2005)
Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden:: Association of susceptibility with PTPN22, CTLA4, and PADI4
RM Plenge et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2005)
Analysis of a functional BTNL2 polymorphism in type 1 diabetes, rheumatoid arthritis, and systemic lupus erythematosus
Gisela Orozco et al.
HUMAN IMMUNOLOGY (2005)
The PTPN22 620W allele is a risk factor for Wegener's granulomatosis
P Jagiello et al.
ARTHRITIS AND RHEUMATISM (2005)
The juxtamembrane wedge negatively regulates CD45 function in B cells
ML Hermiston et al.
IMMUNITY (2005)
Genetic influence of PTPN22 R620W polymorphism in tuberculosis
Luis M. Gomez et al.
HUMAN IMMUNOLOGY (2005)
Maintenance of B cell anergy requires constant antigen receptor occupancy and signaling
SB Gauld et al.
NATURE IMMUNOLOGY (2005)
A case-control study of tyrosine phosphatase (PTPN22) confirms the lack of association with Crohn's disease
SEN Wagenleiter et al.
INTERNATIONAL JOURNAL OF IMMUNOGENETICS (2005)
A general autoimmunity gene (PTPN22) is not associated with inflammatory bowel disease in a British population
NJ Prescott et al.
TISSUE ANTIGENS (2005)
The functional genetic variation in the PTPN22 gene has a negligible effect on the susceptibility to develop inflammatory bowel disease
MC Martín et al.
TISSUE ANTIGENS (2005)
Type 1 diabetes - Evidence for susceptibility loci from four genome-wide linkage scans in 1,435 multiplex families
P Concannon et al.
DIABETES (2005)
PTPN22 genetic variation:: Evidence for multiple variants associated with rheumatoid arthritis
VEH Carlton et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2005)
A single-nucleotide polymorphism in the gene encoding lymphoid protein tyrosine phosphatase (PTPN22) confers susceptibility to generalised vitiligo
I Cantón et al.
GENES AND IMMUNITY (2005)
Association of the lymphoid tyrosine phosphatase R620W variant with rheumatoid arthritis, but not Crohn's disease, in Canadian populations
M van Oene et al.
ARTHRITIS AND RHEUMATISM (2005)
C1858T functional variant of PTPN22 gene is not associated with celiac disease genetic predisposition
B Rueda et al.
HUMAN IMMUNOLOGY (2005)
Lymphoid tyrosine phosphatase (PTPN22/LYP) variant and Graves' disease in a Polish population:: association and gene dose-dependent correlation with age of onset
A Skórka et al.
CLINICAL ENDOCRINOLOGY (2005)
SHP1 expression in bone marrow biopsies of myelodysplastic syndrome patients: a new prognostic factor
AV Mena-Duran et al.
BRITISH JOURNAL OF HAEMATOLOGY (2005)
Association between the PTPN22 gene and rheumatoid arthritis and juvenile idiopathic arthritis in a UK population -: Further support that PTPN22 is an autoimmunity gene
A Hinks et al.
ARTHRITIS AND RHEUMATISM (2005)
Deficiency of the Src homology region 2 domain-containing phosphatase 1 (SHP-1) causes enrichment of CD4+CD25+ regulatory T cells
JD Carter et al.
JOURNAL OF IMMUNOLOGY (2005)
STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes
Q Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Association analysis of the 1858C>T polymorphism in the PTPN22 gene in juvenile idiopathic arthritis and other autoimmune diseases
MK Viken et al.
GENES AND IMMUNITY (2005)
Analysis of families in the multiple autoimmune disease genetics consortium (MADGC) collection:: the PTPN22 620W allele associates with multiple autoimmune phenotypes
LA Criswell et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2005)
Specific inactivation and nuclear anchoring of extracellular signal-regulated kinase 2 by the inducible dual-specificity protein phosphatase DUSP5
M Mandl et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
The PTPN22 R620W polymorphism associates with RF positive rheumatoid arthritis in a dose-dependent manner but not with HLA-SE status
AT Lee et al.
GENES AND IMMUNITY (2005)
Regulatory T cell lineage specification by the forkhead transcription factor FoxP3
JD Fontenot et al.
IMMUNITY (2005)
B cell selection and susceptibility to autoimmunity
C Grimaldi et al.
JOURNAL OF IMMUNOLOGY (2005)
Structural basis for the function and regulation of the receptor protein tyrosine phosphatase CD45
HJ Nam et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Protein tyrosine phosphatases and the immune response
T Mustelin et al.
NATURE REVIEWS IMMUNOLOGY (2005)
The R620W polymorphism of the protein tyrosine phosphatase PTPN22 is not associated with multiple sclerosis
AB Begovich et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2005)
Association of the single nucleotide polymorphism C1858T of the PTPN22 gene with type I diabetes
MB Ladner et al.
HUMAN IMMUNOLOGY (2005)
Rheumatoid arthritis seropositive for the rheumatoid factor is linked to the protein tyrosine phosphatase nonreceptor 22-620W allele
P Dieude et al.
ARTHRITIS RESEARCH & THERAPY (2005)
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
N Bottini et al.
NATURE GENETICS (2004)
被撤回的出版物: Mutual regulation of protein-tyrosine phosphatase 20 and protein-tyrosine kinase Tec activities by tyrosine phosphorylation and dephosphorylation (Retracted Article. See vol 285, pg 32678, 2010)
N Aoki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The innate immune response to pneumococcal lung infection: the untold story
A Kadioglu et al.
TRENDS IN IMMUNOLOGY (2004)
PEST domain-enriched tyrosine phosphatase (PEP) regulation of effector/memory T cells
K Hasegawa et al.
SCIENCE (2004)
Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE
C Kyogoku et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2004)
Regulation of innate and adaptive immune responses by MAP kinase phosphatase 5
YL Zhang et al.
NATURE (2004)
A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis
AB Begovich et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2004)
NMR-based techniques in the hit identification and optimisation processes
M Pellecchia et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2004)
A functional polymorphism (1858C/T) in the PTPN22 gene is linked and associated with type 1 diabetes in multiplex families
S Onengut-Gumuscu et al.
GENES AND IMMUNITY (2004)
Protein tyrosine phosphatases in the human genome
A Alonso et al.
CELL (2004)
The codon 620 tryptophan allele of the lymphoid tyrosine phosphatase (LYP) gene is a major determinant of Graves' disease
MR Velaga et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)
Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus
D Smyth et al.
DIABETES (2004)
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
N Sakaguchi et al.
NATURE (2003)
Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway
NG Shoham et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Activation of ERK induces phosphorylation of MAPK phosphatase-7, a JNK specific phosphatase, at Ser-446
K Masuda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
H Ueda et al.
NATURE (2003)
FAP-1 association with Fas (Apo-1) inhibits Fas expression on the cell surface
VN Ivanov et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
PAC1 phosphatase is a transcription target of p53 in signalling apoptosis and growth suppression
YX Yin et al.
NATURE (2003)
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
JD Fontenot et al.
NATURE IMMUNOLOGY (2003)
Enhanced frequency of a PTPRC (CD45) exon A mutation (77C→G) in systemic sclerosis
R Schwinzer et al.
GENES AND IMMUNITY (2003)
Phosphorylation-dependent regulation of T-cell activation by PAG/Cbp, a lipid raft-associated transmembrane adaptor
D Davidson et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Analysis of γc-family cytokine target genes -: Identification of dual-specificity phosphatase 5 (DUSP5) as a regulator of mitogen-activated protein kinase activity in interleukin-2 signaling
PE Kovanen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Tyrosine phosphorylation of VHR phosphatase by ZAP-70
A Alonso et al.
NATURE IMMUNOLOGY (2003)
77 C/G mutation in the tyrosine phosphatase CD45 gene and autoimmune hepatitis: evidence for a genetic link
A Vogel et al.
GENES AND IMMUNITY (2003)
Arginine methylation of STAT1 regulates its dephosphorylation by T cell protein tyrosine phosphatase
W Zhu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Negative regulation of CD45 by differential homodimerization of the alternatively spliced isoforms
Z Xu et al.
NATURE IMMUNOLOGY (2002)
A recently described polymorphism in the CD28 gene on chromosome 2q33 is not associated with susceptibility to type 1 diabetes
JP Wood et al.
EUROPEAN JOURNAL OF IMMUNOGENETICS (2002)
A novel mutation in PTPRC interferes with splicing and alters the structure of the human CD45 molecule
M Jacobsen et al.
IMMUNOGENETICS (2002)
Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder
CA Wise et al.
HUMAN MOLECULAR GENETICS (2002)
Inhibition of T cell antigen receptor signaling by VHR-related MKPX (VHX), a new dual specificity phosphatase related to VH1 related (VHR)
A Alonso et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
PSTPIP is a substrate of PTP-PEST and serves as a scaffold guiding PTP-PEST toward a specific dephosphorylation of WASP
JF Côté et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The lymphoid protein tyrosine phosphatase Lyp interacts with the adaptor molecule Grb2 and functions as a negative regulator of T-cell activation
RJ Hill et al.
EXPERIMENTAL HEMATOLOGY (2002)
A novel, specific interaction involving the Csk SH3 domain and its natural ligand
R Ghose et al.
NATURE STRUCTURAL BIOLOGY (2001)
Does 77C→G in PTPRC modify autoimmune disorders linked to the major histocompatibility locus?
I Vorechovsky et al.
NATURE GENETICS (2001)
PTPRC (CD45) is not associated with the development of multiple sclerosis in US patients
LF Barcellos et al.
NATURE GENETICS (2001)
A CD45 polymorphism associated with multiple sclerosis disrupts an exonic splicing silencer
KW Lynch et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
MS Jordan et al.
NATURE IMMUNOLOGY (2001)
Identification and allelic frequencies of novel single-nucleotide polymorphisms in the DUSP1 and BTG1 genes
C Suzuki et al.
JOURNAL OF HUMAN GENETICS (2001)
Negative-feedback regulation of CD28 costimulation by a novel mitogen-activated protein kinase phosphatase, MKP6
F Marti et al.
JOURNAL OF IMMUNOLOGY (2001)
Expression of B cell receptor-associated signaling molecules in human lupus
S Hucka et al.
AUTOIMMUNITY (2001)
Protein-tyrosine phosphatase D1, a potential regulator and effector for Tec family kinases
HY Jui et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity
R Majeti et al.
CELL (2000)
A point mutation in PTPRC is associated with the development of multiple sclerosis
M Jacobsen et al.
NATURE GENETICS (2000)
TNFRSF1A mutations and autoinflammatory syndromes
J Galon et al.
CURRENT OPINION IN IMMUNOLOGY (2000)
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