期刊
ANNUAL REVIEW OF GENETICS, VOL 47
卷 47, 期 -, 页码 187-208出版社
ANNUAL REVIEWS
DOI: 10.1146/annurev-genet-110711-155527
关键词
imprinting; DNA demethylation; Polycomb; transposable elements; plant reproduction
资金
- Direct For Biological Sciences
- Div Of Molecular and Cellular Bioscience [1121952] Funding Source: National Science Foundation
Imprinted gene expression-the biased expression of alleles dependent on their parent of origin-is an important type of epigenetic gene regulation in flowering plants and mammals. In plants, genes are imprinted primarily in the endosperm, the triploid placenta-like tissue that surrounds and nourishes the embryo during its development. Differential allelic expression is correlated with active DNA demethylation by DNA glycosylases and repressive targeting by the Polycomb group proteins. Imprinted gene expression is one consequence of a large-scale remodeling to the epigenome, primarily directed at transposable elements, that occurs in gametes and seeds. This remodeling could be important for maintaining the epigenome in the embryo as well as for establishing gene imprinting.
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