Acute central serous chorioretinopathy and fundus autofluorescence

Objectives: To describe fundus autofluorescence (FAF) in a series of patients with acute central serous chorioretinopathy (CSC). Methods: Nine eyes of six patients with acute CSC were evaluated with fluorescein angiography (FA) and FAF imaging to evaluate the nature of the focal retinal pigment epithelial (RPE) leak evident with FA. Results: All nine eyes in this series demonstrated hypoautofluorescence corresponding precisely to the site of the focal RPE leak seen on FA. Conclusions: In this group of patients, the acute focal RPE leaks seen with FA corresponded precisely to an area of hypoautofluorescence imaged with FAF. This observation supports the concept that a mechanical defect or absence of the RIPE accounts for the leakage from the inner choroid to the subneurosensory space in CSC. FAF is also a useful noninvasive diagnostic adjunct to identify the focal RIDE leak in patients with acute CSC.