期刊
ANNUAL REVIEW OF BIOPHYSICS, VOL 40
卷 40, 期 -, 页码 243-266出版社
ANNUAL REVIEWS
DOI: 10.1146/annurev.biophys.093008.131331
关键词
cation pumps; lipid flippases; structure; regulation
类别
P-type ATPases form a large superfamily of cation and lipid pumps. They are remarkably simple with only a single catalytic subunit and carry out large domain motions during transport. The atomic structure of P-type ATPases in different conformations, together with ample mutagenesis evidence, has provided detailed insights into the pumping mechanism by these biological nanomachines. Phylogenetically, P-type ATPases are divided into five subfamilies, P1-P5. These subfamilies differ with respect to transported ligands and the way they are regulated.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据